PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7MFG

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
E	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	92.3	H1	13	H1-13-*	-1	KASGGTFSSYGIS	BBBLBBBBABBBB
E	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	70.0	H2	10	H2-10-*	-1	GIIGMFGTTN	BBBEAALBBB
E	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	100.0	H3	13	H3-13-*	-1	ARGGSYYVDYFHH	BBALBABABBBAB
E	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	87.5	H4	8	H4-8-1	13	ADEFTSTA	BBAAALBB
F	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	91.7	L1	12	L1-12-1	16	RASQSVSsSSLA	BBABBBBAAABB
F	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	18	YGASSRAT	BLLABBBB
F	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	85.7	L3	9	L3-9-*	-1	QQYGSSSGT	BBBABLBBB
F	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	83.3	L4	6	L4-6-*	-1	GFGTDF	EBEAAB
H	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	92.3	H1	13	H1-13-*	-1	KASGGTFSSYGIS	BBBLBBBBABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	70.0	H2	10	H2-10-*	-1	GIIGMFGTTN	BBBEAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	100.0	H3	13	H3-13-*	-1	ARGGSYYVDYFHH	BBALBABABBBAB
H	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	87.5	H4	8	H4-8-1	13	ADEFTSTA	BBAAALBB
J	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	92.3	H1	13	H1-13-*	-1	KASGGTFSSYGIS	BBBLBBBBABBBB
J	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	70.0	H2	10	H2-10-*	-1	GIIGMFGTTN	BBBEAALBBB
J	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	100.0	H3	13	H3-13-*	-1	ARGGSYYVDYFHH	BBALBABABBBAB
J	heavy	Homo.sapiens	Hu_IGHV1-69*01	98.6	Hu_IGHV1-69*01	87.5	H4	8	H4-8-1	13	ADEFTSTA	BBAAALBB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	91.7	L1	12	L1-12-1	16	RASQSVSsSSLA	BBABBBBAAABB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	18	YGASSRAT	BLLABBBB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	85.7	L3	9	L3-9-*	-1	QQYGSSSGT	BBBABLBBB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	83.3	L4	6	L4-6-*	-1	GFGTDF	EBEAAB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	91.7	L1	12	L1-12-1	15	RASQSVSsSSLA	BBABBBBAAABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	18	YGASSRAT	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	85.7	L3	9	L3-9-*	-1	QQYGSSSGT	BBBABLBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	88.4	Hu_IGKV3-20*01	83.3	L4	6	L4-6-*	-1	GFGTDF	EBEAAB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022