PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7MDU

#CDRs = 8; #Clusters = 15.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
E	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	53.8	H1	13	H1-13-1	13	RASGYTFSSFAMS	BBBLBBAAABBBB
E	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	50.0	H2	10	H2-10-2	12	LINDRGGLTF	BBBAALABBB
E	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	33.3	H3	18	H3-18-*	-1	ATGGMssalQSSKYYFDF
E	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	62.5	H4	8	H4-8-1	8	RDNSKNTL	BBAAALBB
F	lambda	Macaca.mulatta	Ma_IGLV2S1*01	97.1	Ma_IGLV2S1*01	92.9	L1	14	L1-14-2	19	TGTSSDIGSyNYVS	BBBAAAAAABBBBB
F	lambda	Macaca.mulatta	Ma_IGLV2S1*01	97.1	Ma_IGLV2S1*01	75.0	L2	8	L2-8-4	13	YDVTQRPS	BEAABBBB
F	lambda	Macaca.mulatta	Ma_IGLV2S1*01	97.1	Ma_IGLV2S1*01	66.7	L3	11	L3-11-*	-1	SAYAGRQTFYI	BBBAEAABABB
F	lambda	Macaca.mulatta	Ma_IGLV2S1*01	97.1	Ma_IGLV2S1*01	100.0	L4	6	L4-6-2	16	KSGNTA	BBEABB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	91.8	Ma_IGHV4-2*01	61.5	H1	13	H1-13-*	-1	AVSGGSFSGYSWG	BBBLBBAAABBBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	91.8	Ma_IGHV4-2*01	50.0	H2	10	H2-10-1	10	SIIGRTGSTA	BBBAAALBBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	91.8	Ma_IGHV4-2*01	100.0	H3	9	H3-9-*	-1	ARQQSNFDF	BBBBEBBAB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	91.8	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	11	RDTSNNQF	BBAAALBB
L	kappa	Macaca.mulatta	Ma_IGKV1S14*01	92.8	Ma_IGKV1S14*01	81.8	L1	11	L1-11-*	-1	RASQDISNDLA	BBABBBBLBBB
L	kappa	Macaca.mulatta	Ma_IGKV1S14*01	92.8	Ma_IGKV1S14*01	100.0	L2	8	L2-8-*	-1	YYASNLES	ABAABBBB
L	kappa	Macaca.mulatta	Ma_IGKV1S14*01	92.8	Ma_IGKV1S14*01	85.7	L3	9	L3-9-2	29	QQYNSYPRT	BBAABABBB
L	kappa	Macaca.mulatta	Ma_IGKV1S14*01	92.8	Ma_IGKV1S14*01	100.0	L4	6	L4-6-1	10	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022