PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7MDT

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Macaca.mulatta	Ma_IGHV3-7*01	84.9	Ma_IGHV3-7*01	61.5	H1	13	H1-13-1	22	EASGFTFGRDDMA	BBBLBBAAABBBB
H	heavy	Macaca.mulatta	Ma_IGHV3-7*01	84.9	Ma_IGHV3-7*01	70.0	H2	10	H2-10-2	7	SISNSGNTIY	BBBAALABBB
H	heavy	Macaca.mulatta	Ma_IGHV3-7*01	84.9	Ma_IGHV3-7*01	100.0	H3	10	H3-10-*	-1	TRTLGDYYLD	BBBBBLBBAB
H	heavy	Macaca.mulatta	Ma_IGHV3-7*01	84.9	Ma_IGHV3-7*01	100.0	H4	8	H4-8-*	-1	RDNAKNSL	BALAALBB
L	lambda	Macaca.mulatta	Ma_IGLV1-15*01	98.5	Ma_IGLV1-15*01	84.6	L1	13	L1-13-1	13	SGSSANIGSTSVS	BBBAAAAAABBBB
L	lambda	Macaca.mulatta	Ma_IGLV1-15*01	98.5	Ma_IGLV1-15*01	100.0	L2	8	L2-8-1	6	YYNDQRAS	BLEABBBB
L	lambda	Macaca.mulatta	Ma_IGLV1-15*01	98.5	Ma_IGLV1-15*01	88.9	L3	11	L3-11-*	-1	AAWDDNLSGRI	BBBBAABBEBB
L	lambda	Macaca.mulatta	Ma_IGLV1-15*01	98.5	Ma_IGLV1-15*01	100.0	L4	6	L4-6-2	18	KSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022