PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7M7W

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV1-69*08	95.9	Hu_IGHV1-69*08	76.9	H1	13	H1-13-*	-1	KASGGIFNTYTIS	BBBEEAAABABBB
A	heavy	Homo.sapiens	Hu_IGHV1-69*08	95.9	Hu_IGHV1-69*08	60.0	H2	10	H2-10-1	9	RIILMSGMAN	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV1-69*08	95.9	Hu_IGHV1-69*08	100.0	H3	19	H3-19-*	-1	ARGFNGNYYgwgddDAFDI
A	heavy	Homo.sapiens	Hu_IGHV1-69*08	95.9	Hu_IGHV1-69*08	100.0	H4	8	H4-8-1	7	ADKSTSTA	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	98.5	Hu_IGLV1-40*01	92.9	L1	14	L1-14-3	11	TGSNSNIGAgYDVH	BBBAABAAALBBBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	98.5	Hu_IGLV1-40*01	87.5	L2	8	L2-8-1	11	CGNSNRPS	BLEABBBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	98.5	Hu_IGLV1-40*01	100.0	L3	13	L3-13-*	-1	QSYDSSLSgpNWV	BBBBAABABBBBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	98.5	Hu_IGLV1-40*01	100.0	L4	6	L4-6-2	9	KSGTSA	BBEABB
C	heavy	Homo.sapiens	Hu_IGHV5-51*01	94.5	Hu_IGHV5-51*01	100.0	H1	13	H1-13-1	10	KGSGYSFTSYWIG	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV5-51*01	94.5	Hu_IGHV5-51*01	100.0	H2	10	H2-10-1	16	IIYPGDSDTR	BBBAAALBBB
C	heavy	Homo.sapiens	Hu_IGHV5-51*01	94.5	Hu_IGHV5-51*01	100.0	H3	13	H3-13-2	18	ARQWSHYTYDYYY	BBBABAABABBAB
C	heavy	Homo.sapiens	Hu_IGHV5-51*01	94.5	Hu_IGHV5-51*01	87.5	H4	8	H4-8-1	14	ADKSISTV	BBAAALBB
D	lambda	Homo.sapiens	Hu_IGLV2-14*01	98.5	Hu_IGLV2-14*01	85.7	L1	14	L1-14-*	-1	TGISSDVGgYNSVS	BLBBBBAABBBBBB
D	lambda	Homo.sapiens	Hu_IGLV2-14*01	98.5	Hu_IGLV2-14*01	75.0	L2	8	L2-8-1	15	YDVTNRPS	BLLABBBB
D	lambda	Homo.sapiens	Hu_IGLV2-14*01	98.5	Hu_IGLV2-14*01	88.9	L3	12	L3-12-*	-1	SSYTSSSTpPYV
D	lambda	Homo.sapiens	Hu_IGLV2-14*01	98.5	Hu_IGLV2-14*01	100.0	L4	6	L4-6-2	17	KSGNTA	BBEABB
E	heavy	Homo.sapiens	Hu_IGHV5-51*01	94.5	Hu_IGHV5-51*01	100.0	H1	13	H1-13-1	10	KGSGYSFTSYWIG	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV5-51*01	94.5	Hu_IGHV5-51*01	100.0	H2	10	H2-10-1	14	IIYPGDSDTR	BBBAAALBBB
E	heavy	Homo.sapiens	Hu_IGHV5-51*01	94.5	Hu_IGHV5-51*01	100.0	H3	13	H3-13-2	18	ARQWSHYTYDYYY	BBBABAABABBAB
E	heavy	Homo.sapiens	Hu_IGHV5-51*01	94.5	Hu_IGHV5-51*01	87.5	H4	8	H4-8-1	16	ADKSISTV	BBAAALBB
F	lambda	Homo.sapiens	Hu_IGLV2-14*01	98.5	Hu_IGLV2-14*01	85.7	L1	14	L1-14-*	-1	TGISSDVGgYNSVS	BLBBBBAABBBBBB
F	lambda	Homo.sapiens	Hu_IGLV2-14*01	98.5	Hu_IGLV2-14*01	75.0	L2	8	L2-8-1	15	YDVTNRPS	BLEABBBB
F	lambda	Homo.sapiens	Hu_IGLV2-14*01	98.5	Hu_IGLV2-14*01	88.9	L3	12	L3-12-*	-1	SSYTSSSTpPYV
F	lambda	Homo.sapiens	Hu_IGLV2-14*01	98.5	Hu_IGLV2-14*01	100.0	L4	6	L4-6-2	15	KSGNTA	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	95.9	Hu_IGHV1-69*08	76.9	H1	13	H1-13-*	-1	KASGGIFNTYTIS	BBAAEAAABABBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	95.9	Hu_IGHV1-69*08	60.0	H2	10	H2-10-1	14	RIILMSGMAN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	95.9	Hu_IGHV1-69*08	100.0	H3	19	H3-19-*	-1	ARGFNGNYYgwgddDAFDI
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	95.9	Hu_IGHV1-69*08	100.0	H4	8	H4-8-1	15	ADKSTSTA	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	98.5	Hu_IGLV1-40*01	92.9	L1	14	L1-14-3	16	TGSNSNIGAgYDVH	BBBAAAAAALBBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	98.5	Hu_IGLV1-40*01	87.5	L2	8	L2-8-*	-1	CGNSNRPS	BEAABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	98.5	Hu_IGLV1-40*01	100.0	L3	13	L3-13-*	-1	QSYDSSLSgpNWV	BBBBAABABBBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	98.5	Hu_IGLV1-40*01	100.0	L4	6	L4-6-2	13	KSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022