PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7M2H

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Mus.musculus	Mo_IGHV1S81*02	90.4	Mo_IGHV1S81*02	84.6	H1	13	H1-13-*	-1	KASGYTFTSDWIH	BBBEBBBAABBBB
A	heavy	Mus.musculus	Mo_IGHV1S81*02	90.4	Mo_IGHV1S81*02	70.0	H2	10	H2-10-1	11	EIIPSYGRAN	BBBAAALBBB
A	heavy	Mus.musculus	Mo_IGHV1S81*02	90.4	Mo_IGHV1S81*02	100.0	H3	11	H3-11-*	-1	ARERGDGYFAV	BBBALALBBAB
A	heavy	Mus.musculus	Mo_IGHV1S81*02	90.4	Mo_IGHV1S81*02	87.5	H4	8	H4-8-1	9	ADKSSSTA	BBAAALBB
B	kappa	Mus.musculus	Mo_IGKV5-48*01	98.6	Mo_IGKV5-48*01	90.9	L1	11	L1-11-1	9	RASQSIGTDIH	BBABBAEABBB
B	kappa	Mus.musculus	Mo_IGKV5-48*01	98.6	Mo_IGKV5-48*01	100.0	L2	8	L2-8-1	22	KYASESIS	BLEABBBB
B	kappa	Mus.musculus	Mo_IGKV5-48*01	98.6	Mo_IGKV5-48*01	85.7	L3	9	L3-9-cis7-1	7	QQSNRWPFT	BBAABBbBB
B	kappa	Mus.musculus	Mo_IGKV5-48*01	98.6	Mo_IGKV5-48*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
D	heavy	Mus.musculus	Mo_IGHV1S81*02	90.4	Mo_IGHV1S81*02	84.6	H1	13	H1-13-*	-1	KASGYTFTSDWIH	BBBEBBBAABBBB
D	heavy	Mus.musculus	Mo_IGHV1S81*02	90.4	Mo_IGHV1S81*02	70.0	H2	10	H2-10-1	12	EIIPSYGRAN	BBBAAALBBB
D	heavy	Mus.musculus	Mo_IGHV1S81*02	90.4	Mo_IGHV1S81*02	100.0	H3	11	H3-11-*	-1	ARERGDGYFAV	BBBALALBBAB
D	heavy	Mus.musculus	Mo_IGHV1S81*02	90.4	Mo_IGHV1S81*02	87.5	H4	8	H4-8-1	8	ADKSSSTA	BBAAALBB
E	kappa	Mus.musculus	Mo_IGKV5-48*01	98.6	Mo_IGKV5-48*01	90.9	L1	11	L1-11-1	7	RASQSIGTDIH	BBABBAEABBB
E	kappa	Mus.musculus	Mo_IGKV5-48*01	98.6	Mo_IGKV5-48*01	100.0	L2	8	L2-8-1	17	KYASESIS	BLLABBBB
E	kappa	Mus.musculus	Mo_IGKV5-48*01	98.6	Mo_IGKV5-48*01	85.7	L3	9	L3-9-cis7-1	7	QQSNRWPFT	BBAABBbBB
E	kappa	Mus.musculus	Mo_IGKV5-48*01	98.6	Mo_IGKV5-48*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022