PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7LY2

#CDRs = 8; #Clusters = 14.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	6	RASQSVSsSYLA	BBABBBBAAABB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	6	YGASSRAT	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	85.7	L3	9	L3-9-1	17	QQYGSSAWT	BBBELLBBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	13	GSGTDF	EBEABB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	6	RASQSVSsSYLA	BBABBBBAAABB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	6	YGASSRAT	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	85.7	L3	9	L3-9-1	17	QQYGSSAWT	BBBELLBBB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	13	GSGTDF	EBEABB
E	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H1	13	H1-13-1	8	KASGYTFTGYYMH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	70.0	H2	10	H2-10-1	11	WINPISSGTS	BBBAAALBBB
E	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H3	18	H3-18-*	-1	ARAAPFydfwSGYSYFDY
E	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	75.0	H4	8	H4-8-1	11	SDTSITTA	BBAAALBB
F	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H1	13	H1-13-1	8	KASGYTFTGYYMH	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	70.0	H2	10	H2-10-1	11	WINPISSGTS	BBBAAALBBB
F	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H3	18	H3-18-*	-1	ARAAPFydfwSGYSYFDY
F	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	75.0	H4	8	H4-8-1	11	SDTSITTA	BBAAALBB
G	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H1	13	H1-13-1	7	AASGFTFSSYGMH	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	90.0	H2	10	H2-10-2	9	VIWYDGSNRY	BBBAALABBB
G	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H3	12	H3-12-3	12	ARAVAGEWYFDY	BBBBBLBABBAB
G	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H4	8	H4-8-1	12	RDNSKNTL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H1	13	H1-13-1	7	AASGFTFSSYGMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	90.0	H2	10	H2-10-2	9	VIWYDGSNRY	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H3	12	H3-12-3	12	ARAVAGEWYFDY	BBBBBLBABBAB
H	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H4	8	H4-8-1	12	RDNSKNTL	BBAAALBB
I	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	81.8	L1	11	L1-11-4	15	SGDALAKHYAY	BEAAAAABBBB
I	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	100.0	L2	8	L2-8-*	-1	YKDSERPS	BLLABBBA
I	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	66.7	L3	11	L3-11-2	14	QSADSIGSSWV	BBBBAALABBB
I	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	100.0	L4	6	L4-6-2	6	SSGTTV	BBEABB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	6	RASQSVSsSYLA	BBABBBBAAABB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	6	YGASSRAT	BLLABBBB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	85.7	L3	9	L3-9-1	16	QQYGSSAWT	BBBELLBBB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	97.1	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	13	GSGTDF	EBEABB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	81.8	L1	11	L1-11-4	15	SGDALAKHYAY	BEAAAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	100.0	L2	8	L2-8-*	-1	YKDSERPS	BLLABBBA
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	66.7	L3	11	L3-11-2	14	QSADSIGSSWV	BBBBAALABBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	100.0	L4	6	L4-6-2	6	SSGTTV	BBEABB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H1	13	H1-13-1	8	KASGYTFTGYYMH	BBBLBBAAABBBB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	70.0	H2	10	H2-10-1	11	WINPISSGTS	BBBAAALBBB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	100.0	H3	18	H3-18-*	-1	ARAAPFydfwSGYSYFDY
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	95.8	Hu_IGHV1-2*02	75.0	H4	8	H4-8-1	11	SDTSITTA	BBAAALBB
N	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H1	13	H1-13-1	7	AASGFTFSSYGMH	BBBLBBAAABBBB
N	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	90.0	H2	10	H2-10-2	9	VIWYDGSNRY	BBBAALABBB
N	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H3	12	H3-12-3	12	ARAVAGEWYFDY	BBBBBLBABBAB
N	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.2	Hu_IGHV3-33*01	100.0	H4	8	H4-8-1	12	RDNSKNTL	BBAAALBB
O	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	81.8	L1	11	L1-11-4	15	SGDALAKHYAY	BEAAAAABBBB
O	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	100.0	L2	8	L2-8-*	-1	YKDSERPS	BLLABBBA
O	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	66.7	L3	11	L3-11-2	14	QSADSIGSSWV	BBBBAALABBB
O	lambda	Homo.sapiens	Hu_IGLV3-25*02	98.5	Hu_IGLV3-25*02	100.0	L4	6	L4-6-2	6	SSGTTV	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022