PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7LBE

#CDRs = 8; #Clusters = 11.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
E	kappa	Homo.sapiens	Hu_IGKV1-27*01	97.1	Hu_IGKV1-27*01	90.9	L1	11	L1-11-*	-1	RASQGINNYLA	BBABBBBLBBB
E	kappa	Homo.sapiens	Hu_IGKV1-27*01	97.1	Hu_IGKV1-27*01	100.0	L2	8	L2-8-1	14	YAASTLQS	BLLABBBB
E	kappa	Homo.sapiens	Hu_IGKV1-27*01	97.1	Hu_IGKV1-27*01	100.0	L3	9	L3-9-cis7-1	23	QKYNSAPFT	BBAABBbBB
E	kappa	Homo.sapiens	Hu_IGKV1-27*01	97.1	Hu_IGKV1-27*01	83.3	L4	6	L4-6-1	9	GSGTAF	EBEABB
F	heavy	Homo.sapiens	Hu_IGHV1-46*01	97.3	Hu_IGHV1-46*01	84.6	H1	13	H1-13-1	9	KASGYTFTNYYIH	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV1-46*01	97.3	Hu_IGHV1-46*01	70.0	H2	10	H2-10-1	7	IIHPSSGGTS	BBBAAALBBB
F	heavy	Homo.sapiens	Hu_IGHV1-46*01	97.3	Hu_IGHV1-46*01	50.0	H3	16	H3-16-*	-1	GRAFRILglSDVFVND
F	heavy	Homo.sapiens	Hu_IGHV1-46*01	97.3	Hu_IGHV1-46*01	100.0	H4	8	H4-8-1	8	RDTSTSTV	BBAAALBB
G	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Hu_IGKV2-28*01	93.8	L1	16	L1-16-1	13	RSSQSLlhtngYNYLD	BBABBABBAALBBBBB
G	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Hu_IGKV2-28*01	87.5	L2	8	L2-8-1	15	YLASNRAS	BLLABBBB
G	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Hu_IGKV2-28*01	85.7	L3	9	L3-9-cis7-1	13	MQALQIPRT	BBAABBbBB
G	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Hu_IGKV2-28*01	100.0	L4	6	L4-6-1	13	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	93.0	Hu_IGHV3-21*01	76.9	H1	13	H1-13-1	18	AASGFTFSPYSVF	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	93.0	Hu_IGHV3-21*01	60.0	H2	10	H2-10-2	11	SINSDSTYKY	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	93.0	Hu_IGHV3-21*01	100.0	H3	23	H3-23-*	-1	ARDRSYYafssgslsdYYYGLDV
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	93.0	Hu_IGHV3-21*01	75.0	H4	8	H4-8-1	12	RDNAENSI	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022