PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7L6M

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
g	kappa	Macaca.mulatta	Ma_IGKV2S10*01	79.7	Ma_IGKV2S10*01	87.5	L1	16	L1-16-*	-1	RSSASLlhgngNTYLH	BBABBABBEALBBBBB
g	kappa	Macaca.mulatta	Ma_IGKV2S10*01	79.7	Ma_IGKV2S10*01	50.0	L2	8	L2-8-1	22	FGGSKRVP	BLEABBBB
g	kappa	Macaca.mulatta	Ma_IGKV2S10*01	79.7	Ma_IGKV2S10*01	57.1	L3	9	L3-9-*	-1	AQGVAFPWT	BBBAABABB
g	kappa	Macaca.mulatta	Ma_IGKV2S10*01	79.7	Ma_IGKV2S10*01	66.7	L4	6	L4-6-3	29	GAGTNF	BBAABB
h	heavy	Macaca.mulatta	Ma_IGHV1-1*01	60.0	Ma_IGHV1-1*01	61.5	H1	13	H1-13-*	-1	QASNYTFPDYYIH	BBBBBBAAABBBB
h	heavy	Macaca.mulatta	Ma_IGHV1-1*01	60.0	Ma_IGHV1-1*01	20.0	H2	10	H2-10-*	-1	EMKPKVGVTN	BBBAAAEBAB
h	heavy	Macaca.mulatta	Ma_IGHV1-1*01	60.0	Ma_IGHV1-1*01	100.0	H3	13	H3-13-*	-1	TRLEPDFLSGWAH	BBBABAAAALBBB
h	heavy	Macaca.mulatta	Ma_IGHV1-1*01	60.0	Ma_IGHV1-1*01	62.5	H4	8	H4-8-1	11	ADTSTDTA	BBAAALBB
i	heavy	Macaca.mulatta	Ma_IGHV1-1*01	60.0	Ma_IGHV1-1*01	61.5	H1	13	H1-13-*	-1	QASNYTFPDYYIH	BBBBBBAAABBBB
i	heavy	Macaca.mulatta	Ma_IGHV1-1*01	60.0	Ma_IGHV1-1*01	20.0	H2	10	H2-10-*	-1	EMKPKVGVTN	BBBAAALBBB
i	heavy	Macaca.mulatta	Ma_IGHV1-1*01	60.0	Ma_IGHV1-1*01	100.0	H3	13	H3-13-*	-1	TRLEPDFLSGWAH	BBBBAAAAAABBB
i	heavy	Macaca.mulatta	Ma_IGHV1-1*01	60.0	Ma_IGHV1-1*01	62.5	H4	8	H4-8-*	-1	ADTSTDTA	BBAAALBB
j	kappa	Macaca.mulatta	Ma_IGKV2S10*01	79.7	Ma_IGKV2S10*01	87.5	L1	16	L1-16-*	-1	RSSASLlhgngNTYLH	BBABBBBAELLBBBBB
j	kappa	Macaca.mulatta	Ma_IGKV2S10*01	79.7	Ma_IGKV2S10*01	50.0	L2	8	L2-8-*	-1	FGGSKRVP	ABEABBBB
j	kappa	Macaca.mulatta	Ma_IGKV2S10*01	79.7	Ma_IGKV2S10*01	57.1	L3	9	L3-9-cis7-*	-1	AQGVAFPWT	BALBBBbBB
j	kappa	Macaca.mulatta	Ma_IGKV2S10*01	79.7	Ma_IGKV2S10*01	66.7	L4	6	L4-6-1	19	GAGTNF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022