PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7KQK

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Ch_IGHV1S1*01	69.2	H1	13	H1-13-1	10	AASGFTLSSYQMM	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Ch_IGHV1S1*01	50.0	H2	10	H2-10-2	8	GITGRGGVTG	BBBAALABBB
A	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Hu_IGHV3-23*05	100.0	H3	20	H3-20-*	-1	AKPALDSDQCGFpeagciDA
A	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Hu_IGHV3-23*05	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV3-19*02	98.5	Ch_IGLV1-1*01	75.0	L1	8	L1-8-*	-1	QGDDSYYG	BBBLBBBB
B	lambda	Homo.sapiens	Hu_IGLV3-19*02	98.5	Ch_IGLV1-1*01	75.0	L2	8	L2-8-1	8	YGNDNRPS	BLLABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-19*02	98.5	Hu_IGLV3-19*02	44.4	L3	11	L3-11-1	17	GAYDSSGGGGI	BBBBAAALBBB
B	lambda	Homo.sapiens	Hu_IGLV3-19*02	98.5	Hu_IGLV3-19*02	100.0	L4	6	L4-6-*	-1	SSGNTA	BBBLBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Ch_IGHV1S1*01	69.2	H1	13	H1-13-1	11	AASGFTLSSYQMM	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Ch_IGHV1S1*01	50.0	H2	10	H2-10-2	9	GITGRGGVTG	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Hu_IGHV3-23*05	100.0	H3	20	H3-20-*	-1	AKPALDSDQCGFpeagciDA
H	heavy	Homo.sapiens	Hu_IGHV3-23*05	98.6	Hu_IGHV3-23*05	100.0	H4	8	H4-8-1	6	RDNSKNTL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-19*02	98.5	Ch_IGLV1-1*01	75.0	L1	8	L1-8-*	-1	QGDDSYYG	BBBBBBBB
L	lambda	Homo.sapiens	Hu_IGLV3-19*02	98.5	Ch_IGLV1-1*01	75.0	L2	8	L2-8-1	7	YGNDNRPS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-19*02	98.5	Hu_IGLV3-19*02	44.4	L3	11	L3-11-1	17	GAYDSSGGGGI	BBBBAAALBBB
L	lambda	Homo.sapiens	Hu_IGLV3-19*02	98.5	Hu_IGLV3-19*02	100.0	L4	6	L4-6-2	15	SSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022