PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7KHF

#CDRs = 8; #Clusters = 10.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV2-5*04	89.0	Hu_IGHV2-5*04	80.0	H1	15	H1-15-1	21	TFSGFSLTTDglGVG	BBBLBBAABBLBBBB
A	heavy	Homo.sapiens	Hu_IGHV2-5*04	89.0	Hu_IGHV2-5*04	55.6	H2	9	H2-9-*	-1	LIYYDDVRR	BBBABBBBB
A	heavy	Homo.sapiens	Hu_IGHV2-5*04	89.0	Hu_IGHV2-5*04	100.0	H3	17	H3-17-*	-1	VHASLfnlGSRNVYFRY
A	heavy	Homo.sapiens	Hu_IGHV2-5*04	89.0	Hu_IGHV2-5*04	87.5	H4	8	H4-8-1	14	KDTSKNRV	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV3-25*02	89.6	Hu_IGLV3-25*02	54.5	L1	11	L1-11-4	18	SGDSLARQFAS	BBAAAAABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-25*02	89.6	Hu_IGLV3-25*02	62.5	L2	8	L2-8-*	-1	YKNIERLS	BLLABBBA
B	lambda	Homo.sapiens	Hu_IGLV3-25*02	89.6	Hu_IGLV3-25*02	77.8	L3	11	L3-11-2	17	QSADDSGSYSL	BBBBAALABBB
B	lambda	Homo.sapiens	Hu_IGLV3-25*02	89.6	Hu_IGLV3-25*02	66.7	L4	6	L4-6-2	16	TSGTSV	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV2-5*04	89.0	Hu_IGHV2-5*04	80.0	H1	15	H1-15-1	19	TFSGFSLTTDglGVG	BBBLBBAABBLBEBB
H	heavy	Homo.sapiens	Hu_IGHV2-5*04	89.0	Hu_IGHV2-5*04	55.6	H2	9	H2-9-*	-1	LIYYDDVRR	BBBBBABBB
H	heavy	Homo.sapiens	Hu_IGHV2-5*04	89.0	Hu_IGHV2-5*04	100.0	H3	17	H3-17-*	-1	VHASLfnlGSRNVYFRY
H	heavy	Homo.sapiens	Hu_IGHV2-5*04	89.0	Hu_IGHV2-5*04	87.5	H4	8	H4-8-*	-1	KDTSKNRV	BBAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	89.6	Hu_IGLV3-25*02	54.5	L1	11	L1-11-4	14	SGDSLARQFAS	BBAAAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	89.6	Hu_IGLV3-25*02	62.5	L2	8	L2-8-*	-1	YKNIERLS	BEAABBBA
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	89.6	Hu_IGLV3-25*02	77.8	L3	11	L3-11-*	-1	QSADDSGSYSL	BBBBAALBBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	89.6	Hu_IGLV3-25*02	66.7	L4	6	L4-6-2	13	TSGTSV	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022