PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7KF0

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV14-3*02	84.6	H1	13	H1-13-1	15	AASGFNIKDTYIH	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV14-3*02	60.0	H2	10	H2-10-1	10	RIYPTNGYTR	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	13	H3-13-2	22	ARGGSFYYYYMDV	BBBABAABABBAB
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV3-12*01	33.3	L1	15	L1-15-*	-1	RASQdiprSISGYVA	BBABBBBAABBLABB
B	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV3-12*01	50.0	L2	8	L2-8-1	9	YWGSYLYS	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	42.9	L3	9	L3-9-cis7-1	12	QQHYTTPPT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV14-3*02	84.6	H1	13	H1-13-1	14	AASGFNIKDTYIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV14-3*02	60.0	H2	10	H2-10-1	9	RIYPTNGYTR	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	13	H3-13-*	-1	ARGGSFYYYYMDV	BBALBAABABBAB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV3-12*01	33.3	L1	15	L1-15-*	-1	RASQdiprSISGYVA	BBABBBBAABBLABB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV3-12*01	50.0	L2	8	L2-8-1	9	YWGSYLYS	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	42.9	L3	9	L3-9-cis7-1	12	QQHYTTPPT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	100.0	L4	6	L4-6-1	13	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022