PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7FCP

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
B	heavy	Homo.sapiens	Hu_IGHV3-11*01	94.5	Hu_IGHV3-11*01	69.2	H1	13	H1-13-1	9	AASGFTFRDYDII	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-11*01	94.5	Hu_IGHV3-11*01	90.0	H2	10	H2-10-2	11	YISRSGSTIY	BBBAALABBB
B	heavy	Homo.sapiens	Hu_IGHV3-11*01	94.5	Hu_IGHV3-11*01	100.0	H3	13	H3-13-*	-1	ARDFGFEGPRMDV	BBBAEABBbBLAB
B	heavy	Homo.sapiens	Hu_IGHV3-11*01	94.5	Hu_IGHV3-11*01	87.5	H4	8	H4-8-1	6	RDNAKNSV	BBAAALBB
D	kappa	Homo.sapiens	Hu_IGKV1-33*01	100.0	Hu_IGKV1-33*01	90.9	L1	11	L1-11-1	4	QASQDIKNYLN	BBABBAEABBB
D	kappa	Homo.sapiens	Hu_IGKV1-33*01	100.0	Hu_IGKV1-33*01	100.0	L2	8	L2-8-1	5	YDASNLET	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV1-33*01	100.0	Hu_IGKV1-33*01	85.7	L3	9	L3-9-cis7-1	6	QQFDNlPIT	BBAABBbBB
D	kappa	Homo.sapiens	Hu_IGKV1-33*01	100.0	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	17	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-46*01	97.3	Hu_IGHV1-46*01	84.6	H1	13	H1-13-1	7	KASGYIFTSYSMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-46*01	97.3	Hu_IGHV1-46*01	50.0	H2	10	H2-10-1	10	TIKPSDDSTN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-46*01	97.3	Hu_IGHV1-46*01	100.0	H3	21	H3-21-*	-1	AREARGYYDRsgyyhpgYFDY
H	heavy	Homo.sapiens	Hu_IGHV1-46*01	97.3	Hu_IGHV1-46*01	100.0	H4	8	H4-8-1	6	RDTSTSTV	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*01	97.1	Hu_IGLV2-14*01	92.9	L1	14	L1-14-2	9	TGTSSDVGgYNFVS	BBBAAAAAABABBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*01	97.1	Hu_IGLV2-14*01	87.5	L2	8	L2-8-1	11	YEVSDRPS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*01	97.1	Hu_IGLV2-14*01	55.6	L3	10	L3-10-1	12	FSYTTSTTWV	BBBBAALBBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*01	97.1	Hu_IGLV2-14*01	100.0	L4	6	L4-6-2	7	KSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022