PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7E8C

#CDRs = 8; #Clusters = 17.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	76.9	H1	13	H1-13-1	26	AASGIIVSSNYMT	BBBEBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	88.9	H2	9	H2-9-1	11	VIYSGGSTF	BBBAALBBB
D	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	100.0	H3	11	H3-11-*	-1	ARDLGPYGMDV	BBBAEABBBAB
D	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	87.5	H4	8	H4-8-1	11	RDKSKNTL	BBAAALBB
E	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	90.9	L1	11	L1-11-*	-1	RASQGISSDLA	BBAAEALABBB
E	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	100.0	L2	8	L2-8-1	15	YAASTLQS	BLLABBBB
E	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	71.4	L3	9	L3-9-*	-1	QQLNSDLYT	BBBLBAALB
E	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	83.3	L4	6	L4-6-1	18	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	92.3	H1	13	H1-13-*	-1	AASEFTFSSYSMN	BBABAAAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	80.0	H2	10	H2-10-2	14	SISSSGSQIY	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	50.0	H3	18	H3-18-*	-1	ATNGGahssTWSFYGMDV
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	87.5	H4	8	H4-8-1	12	RDNAKKSL	BBAAALBB
I	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	93.8	L1	16	L1-16-*	-1	RSSQSLLHsngylYLD	BBABBABLAALBBBBB
I	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L2	8	L2-8-1	19	YLGSNRAS	BLLABBBB
I	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L3	9	L3-9-2	12	MQALQTPGT	BBAABABBB
I	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L4	6	L4-6-1	14	GSGTDF	EBEABB
J	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	93.8	L1	16	L1-16-*	-1	RSSQSLLHsngylYLD	BBABBABLAALBBBBB
J	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L2	8	L2-8-1	19	YLGSNRAS	BLLABBBB
J	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L3	9	L3-9-2	12	MQALQTPGT	BBAABABBB
J	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L4	6	L4-6-1	14	GSGTDF	EBEABB
K	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	69.2	H1	13	H1-13-*	-1	AASGFAFTTYAMN	BBBLBALAABBBB
K	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	70.0	H2	10	H2-10-*	-1	AISDGGGSAY	BBBAAEEBBB
K	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	100.0	H3	18	H3-18-*	-1	AKTRGRGLYDYVwgskDY
K	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	100.0	H4	8	H4-8-1	9	RDNSKNTL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L1	11	L1-11-3	9	SGDKLGDKYAC	BBBLAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L2	8	L2-8-1	17	YQDSKRPS	BLLABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	75.0	L3	9	L3-9-1	13	QAWDSNTGV	BBBBLLBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	11	NSGNTA	BBEABB
M	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	69.2	H1	13	H1-13-*	-1	AASGFAFTTYAMN	BBBLBALAABBBB
M	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	70.0	H2	10	H2-10-*	-1	AISDGGGSAY	BBBAAEEBBB
M	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	100.0	H3	18	H3-18-*	-1	AKTRGRGLYDYVwgskDY
M	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	100.0	H4	8	H4-8-1	9	RDNSKNTL	BBAAALBB
N	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	76.9	H1	13	H1-13-1	26	AASGIIVSSNYMT	BBBEBBAAABBBB
N	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	88.9	H2	9	H2-9-1	11	VIYSGGSTF	BBBAALBBB
N	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	100.0	H3	11	H3-11-*	-1	ARDLGPYGMDV	BBBAEABBBAB
N	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	87.5	H4	8	H4-8-1	11	RDKSKNTL	BBAAALBB
O	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	76.9	H1	13	H1-13-1	26	AASGIIVSSNYMT	BBBEBBAAABBBB
O	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	88.9	H2	9	H2-9-1	11	VIYSGGSTF	BBBAALBBB
O	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	100.0	H3	11	H3-11-*	-1	ARDLGPYGMDV	BBBAEABBBAB
O	heavy	Homo.sapiens	Hu_IGHV3-53*01	97.3	Hu_IGHV3-53*01	87.5	H4	8	H4-8-1	11	RDKSKNTL	BBAAALBB
P	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	90.9	L1	11	L1-11-*	-1	RASQGISSDLA	BBAAEALABBB
P	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	100.0	L2	8	L2-8-1	15	YAASTLQS	BLLABBBB
P	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	71.4	L3	9	L3-9-*	-1	QQLNSDLYT	BBBLBAALB
P	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	83.3	L4	6	L4-6-1	18	GSGTDF	EBEABB
Q	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	90.9	L1	11	L1-11-*	-1	RASQGISSDLA	BBAAEALABBB
Q	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	100.0	L2	8	L2-8-1	15	YAASTLQS	BLLABBBB
Q	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	71.4	L3	9	L3-9-*	-1	QQLNSDLYT	BBBLBAALB
Q	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	83.3	L4	6	L4-6-1	18	GSGTDF	EBEABB
S	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	92.3	H1	13	H1-13-*	-1	AASEFTFSSYSMN	BBABAAAAABBBB
S	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	80.0	H2	10	H2-10-2	14	SISSSGSQIY	BBBAALABBB
S	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	50.0	H3	18	H3-18-*	-1	ATNGGahssTWSFYGMDV
S	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	87.5	H4	8	H4-8-1	12	RDNAKKSL	BBAAALBB
T	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	92.3	H1	13	H1-13-*	-1	AASEFTFSSYSMN	BBABAAAAABBBB
T	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	80.0	H2	10	H2-10-2	14	SISSSGSQIY	BBBAALABBB
T	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	50.0	H3	18	H3-18-*	-1	ATNGGahssTWSFYGMDV
T	heavy	Homo.sapiens	Hu_IGHV3-21*01	97.3	Hu_IGHV3-21*01	87.5	H4	8	H4-8-1	12	RDNAKKSL	BBAAALBB
U	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L1	11	L1-11-3	9	SGDKLGDKYAC	BBBLAAABBBB
U	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L2	8	L2-8-1	17	YQDSKRPS	BLLABBBB
U	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	75.0	L3	9	L3-9-1	13	QAWDSNTGV	BBBBLLBBB
U	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	11	NSGNTA	BBEABB
V	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L1	11	L1-11-3	9	SGDKLGDKYAC	BBBLAAABBBB
V	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L2	8	L2-8-1	17	YQDSKRPS	BLLABBBB
V	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	75.0	L3	9	L3-9-1	13	QAWDSNTGV	BBBBLLBBB
V	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	11	NSGNTA	BBEABB
Z	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	93.8	L1	16	L1-16-*	-1	RSSQSLLHsngylYLD	BBABBABLAALBBBBB
Z	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L2	8	L2-8-1	19	YLGSNRAS	BLLABBBB
Z	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L3	9	L3-9-2	12	MQALQTPGT	BBAABABBB
Z	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L4	6	L4-6-1	14	GSGTDF	EBEABB
a	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	69.2	H1	13	H1-13-*	-1	AASGFAFTTYAMN	BBBLBALAABBBB
a	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	70.0	H2	10	H2-10-*	-1	AISDGGGSAY	BBBAAEEBBB
a	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	100.0	H3	18	H3-18-*	-1	AKTRGRGLYDYVwgskDY
a	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	100.0	H4	8	H4-8-1	9	RDNSKNTL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022