PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7CWT

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Mo_IGKV3-2*01	100.0	L1	15	L1-15-*	-1	RASESVDNYgisfMN	BBBEBBEBAALBBEE
D	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Mo_IGKV3-2*01	100.0	L2	8	L2-8-*	-1	YAASNQGS	BLLABEEB
D	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Hu_IGKV3-11*01	42.9	L3	9	L3-9-*	-1	QQSKEVPRI	BBBLBEBAE
D	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Hu_IGKV3-11*01	100.0	L4	6	L4-6-2	25	GSGTDF	BBEABB
E	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Mo_IGHV5-6*01	84.6	H1	13	H1-13-1	22	AASGFTFTNYGMS	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Mo_IGHV5-6*01	90.0	H2	10	H2-10-*	-1	EISSGGSYTY	BBBAABBALB
E	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Hu_IGHV3-7*01	100.0	H3	13	H3-13-*	-1	ARFRYGGGGTVDY	BBBBBBEABbBAB
E	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Hu_IGHV3-7*01	87.5	H4	8	H4-8-1	12	RDNAKNTL	BBAAALBB
F	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Mo_IGKV3-2*01	100.0	L1	15	L1-15-*	-1	RASESVDNYgisfMN	BBBEBBEBAALBBEE
F	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Mo_IGKV3-2*01	100.0	L2	8	L2-8-*	-1	YAASNQGS	BLLABEEB
F	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Hu_IGKV3-11*01	42.9	L3	9	L3-9-*	-1	QQSKEVPRI	BBBLBEBAE
F	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Hu_IGKV3-11*01	100.0	L4	6	L4-6-2	25	GSGTDF	BBEABB
G	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Mo_IGHV5-6*01	84.6	H1	13	H1-13-1	22	AASGFTFTNYGMS	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Mo_IGHV5-6*01	90.0	H2	10	H2-10-*	-1	EISSGGSYTY	BBBAABBALB
G	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Hu_IGHV3-7*01	100.0	H3	13	H3-13-*	-1	ARFRYGGGGTVDY	BBBBBBBAAbBAB
G	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Hu_IGHV3-7*01	87.5	H4	8	H4-8-1	12	RDNAKNTL	BBAAALBB
H	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L1	13	L1-13-1	11	SGSSSNIGNNYVS	BBBAAAAAABBBB
H	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L2	8	L2-8-1	16	YDNNKRPS	BLLABBBB
H	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L3	11	L3-11-1	16	GTWDSSLSAVV	BBBBAAALBBB
H	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	16	KSGTSA	BBEABB
I	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Mo_IGHV5-6*01	84.6	H1	13	H1-13-1	24	AASGFTFTNYGMS	BBBLBBAAABBBB
I	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Mo_IGHV5-6*01	90.0	H2	10	H2-10-*	-1	EISSGGSYTY	BBBABEBALB
I	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Hu_IGHV3-7*01	100.0	H3	13	H3-13-*	-1	ARFRYGGGGTVDY	BBBBBLBAAbBAB
I	heavy	Homo.sapiens	Hu_IGHV3-7*01	90.3	Hu_IGHV3-7*01	87.5	H4	8	H4-8-1	25	RDNAKNTL	BBAAALBB
J	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Mo_IGKV3-2*01	100.0	L1	15	L1-15-*	-1	RASESVDNYgisfMN	BBBEBBEBAALBBEE
J	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Mo_IGKV3-2*01	100.0	L2	8	L2-8-*	-1	YAASNQGS	BLLABEEB
J	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Hu_IGKV3-11*01	42.9	L3	9	L3-9-*	-1	QQSKEVPRI	BBBLBEBAE
J	kappa	Homo.sapiens	Hu_IGKV3-11*01	92.6	Hu_IGKV3-11*01	100.0	L4	6	L4-6-2	25	GSGTDF	BBEABB
K	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L1	13	L1-13-1	11	SGSSSNIGNNYVS	BBBAAAAAABBBB
K	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L2	8	L2-8-1	22	YDNNKRPS	BLLABBBB
K	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L3	11	L3-11-1	16	GTWDSSLSAVV	BBBBAAALBBB
K	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	16	KSGTSA	BBEABB
L	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	76.9	H1	13	H1-13-1	26	KVSGYTLPEVAMH	BBBLBBAAABBBB
L	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	90.0	H2	10	H2-10-*	-1	GFDPEDGETM	EBBABLLBBB
L	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H3	14	H3-14-*	-1	ATTTPFSSSYWFDP	BBBBABaABABAEB
L	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H4	8	H4-8-1	16	EDTSTDTA	BBAAALBB
M	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L1	13	L1-13-1	11	SGSSSNIGNNYVS	BBBAAAAAABBBB
M	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L2	8	L2-8-1	21	YDNNKRPS	BLLABBBB
M	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L3	11	L3-11-1	16	GTWDSSLSAVV	BBBBAAALBBB
M	lambda	Homo.sapiens	Hu_IGLV1-51*01	98.5	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	16	KSGTSA	BBEABB
N	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	76.9	H1	13	H1-13-1	26	KVSGYTLPEVAMH	BBBLBBAAABBBB
N	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	90.0	H2	10	H2-10-*	-1	GFDPEDGETM	EBBABLLBBB
N	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H3	14	H3-14-*	-1	ATTTPFSSSYWFDP	BBBBABaABABAEB
N	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H4	8	H4-8-1	16	EDTSTDTA	BBAAALBB
P	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	76.9	H1	13	H1-13-1	26	KVSGYTLPEVAMH	BBBLBBAAABBBB
P	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	90.0	H2	10	H2-10-*	-1	GFDPEDGETM	EBBABLLBBB
P	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H3	14	H3-14-*	-1	ATTTPFSSSYWFDP	BBBBABaABABAEB
P	heavy	Homo.sapiens	Hu_IGHV1-24*01	97.1	Hu_IGHV1-24*01	100.0	H4	8	H4-8-1	16	EDTSTDTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022