PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7CWN

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	81.8	L1	11	L1-11-*	-1	RASQSISSNLH	BBBEBBBABBB
D	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L2	8	L2-8-1	25	KYASQSIS	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	28.6	L3	9	L3-9-*	-1	QQTNFWPYI	BBBELEBBB
D	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L4	6	L4-6-2	14	GSGTDF	BBEABB
E	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	69.2	H1	13	H1-13-1	14	KVSGYSFSNYYIH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	40.0	H2	10	H2-10-*	-1	YIDPFNGGTS	BBBAABBABB
E	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	50.0	H3	13	H3-13-*	-1	ARSEYDPYYVMDY	BBBBABABBBBAB
E	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	100.0	H4	8	H4-8-1	14	ADTSTDTA	BBAAALBB
F	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L1	11	L1-11-*	-1	RASQSISSYLN	BBABBBAABBB
F	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L2	8	L2-8-*	-1	YAASSLQS	BLLABBBB
F	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L3	9	L3-9-cis7-1	14	QQSYSTPRT	BBAABBbBB
F	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
G	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H1	13	H1-13-1	24	AASGFTFSSYAMH	BBBEBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H2	10	H2-10-*	-1	VISYDGSNKY	BBBAABBBBB
G	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H3	12	H3-12-*	-1	ARHATLMNNKDI	BBBBBLABBABB
G	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	13	RDNSKNTL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	69.2	H1	13	H1-13-1	14	KVSGYSFSNYYIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	40.0	H2	10	H2-10-*	-1	YIDPFNGGTS	BBBAABBABB
H	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	50.0	H3	13	H3-13-*	-1	ARSEYDPYYVMDY	BBBBABABBBBAB
H	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	100.0	H4	8	H4-8-1	14	ADTSTDTA	BBAAALBB
I	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L1	11	L1-11-*	-1	RASQSISSYLN	BBABBBAABBB
I	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L2	8	L2-8-*	-1	YAASSLQS	BLLABBBB
I	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L3	9	L3-9-cis7-1	14	QQSYSTPRT	BBAABBbBB
I	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
J	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L1	11	L1-11-*	-1	RASQSISSYLN	BBABBBAABBB
J	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L2	8	L2-8-*	-1	YAASSLQS	BLLABBBB
J	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L3	9	L3-9-cis7-1	14	QQSYSTPRT	BBAABBbBB
J	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
K	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H1	13	H1-13-1	24	AASGFTFSSYAMH	BBBEBBAAABBBB
K	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H2	10	H2-10-*	-1	VISYDGSNKY	BBBAABBBBB
K	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H3	12	H3-12-*	-1	ARHATLMNNKDI	BBBBBLABBABB
K	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	13	RDNSKNTL	BBAAALBB
L	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H1	13	H1-13-1	24	AASGFTFSSYAMH	BBBEBBAAABBBB
L	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H2	10	H2-10-*	-1	VISYDGSNKY	BBBAABBBBB
L	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H3	12	H3-12-*	-1	ARHATLMNNKDI	BBBBBLABBABB
L	heavy	Homo.sapiens	Hu_IGHV3-30*01	100.0	Hu_IGHV3-30*01	100.0	H4	8	H4-8-1	13	RDNSKNTL	BBAAALBB
M	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	81.8	L1	11	L1-11-*	-1	RASQSISSNLH	BBBEBBBABBB
M	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L2	8	L2-8-1	25	KYASQSIS	BLLABBBB
M	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	28.6	L3	9	L3-9-*	-1	QQTNFWPYI	BBBELEBBB
M	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L4	6	L4-6-2	14	GSGTDF	BBEABB
N	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	81.8	L1	11	L1-11-*	-1	RASQSISSNLH	BBBEBBBABBB
N	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L2	8	L2-8-1	25	KYASQSIS	BLLABBBB
N	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	28.6	L3	9	L3-9-*	-1	QQTNFWPYI	BBBELEBBB
N	kappa	Homo.sapiens	Hu_IGKV6D-21*02	89.7	Hu_IGKV6D-21*02	100.0	L4	6	L4-6-2	14	GSGTDF	BBEABB
O	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	69.2	H1	13	H1-13-1	14	KVSGYSFSNYYIH	BBBLBBAAABBBB
O	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	40.0	H2	10	H2-10-*	-1	YIDPFNGGTS	BBBAABBABB
O	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	50.0	H3	13	H3-13-*	-1	ARSEYDPYYVMDY	BBBBABABBBBAB
O	heavy	Homo.sapiens	Hu_IGHV1-69-2*01	86.1	Hu_IGHV1-69-2*01	100.0	H4	8	H4-8-1	14	ADTSTDTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022