PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 7CHE

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	69.2	H1	13	H1-13-*	-1	AASGFAFTTYAMN	BBBLBAEAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	70.0	H2	10	H2-10-*	-1	AISDGGGSAY	BBBAAELBBB
A	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	100.0	H3	18	H3-18-*	-1	AKTRGRGLYDYVwgskDY
A	heavy	Homo.sapiens	Hu_IGHV3-23*01	97.3	Hu_IGHV3-23*01	100.0	H4	8	H4-8-1	10	RDNSKNTL	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L1	16	L1-16-*	-1	RSSQSLlhsngYNYLD	BBABBABEALLBBBBB
B	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L2	8	L2-8-1	12	YLGSNRAS	BLEABBBB
B	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L3	9	L3-9-2	9	MQALQTPGT	BBAABABBB
B	kappa	Homo.sapiens	Hu_IGKV2-28*01	100.0	Hu_IGKV2-28*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-53*01	98.6	Hu_IGHV3-53*01	92.3	H1	13	H1-13-1	18	AASGITVSSNYMS	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-53*01	98.6	Hu_IGHV3-53*01	88.9	H2	9	H2-9-1	16	VIYSGGSTD	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-53*01	98.6	Hu_IGHV3-53*01	100.0	H3	12	H3-12-*	-1	ARDLGEAGGMDV	BBBAEAAEBBAB
H	heavy	Homo.sapiens	Hu_IGHV3-53*01	98.6	Hu_IGHV3-53*01	87.5	H4	8	H4-8-1	18	RDKSKNTL	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	100.0	L1	11	L1-11-*	-1	RASQGISSYLA	BBAALAEABBB
L	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	100.0	L2	8	L2-8-1	8	YAASTLQS	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	100.0	L3	9	L3-9-*	-1	QQLNSYPPA	BBBLBABBB
L	kappa	Homo.sapiens	Hu_IGKV1-9*01	97.1	Hu_IGKV1-9*01	83.3	L4	6	L4-6-1	10	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022