PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6X7W

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Mus.musculus	Mo_IGHV5-9*01	97.3	Mo_IGHV5-9*01	53.8	H1	13	H1-13-1	10	EASGFSFGFYSLS	BBBLBBAAABBBB
A	heavy	Mus.musculus	Mo_IGHV5-9*01	97.3	CDRLenMismatch	-1.0	H2	12	H2-12-1	20	TIAGSgvGGQTY	BBBBAAALLBBB
A	heavy	Mus.musculus	Mo_IGHV5-9*01	97.3	Mo_IGHV5-9*01	100.0	H3	14	H3-14-*	-1	ARHGEGKYGSNFAY	BBBBBEABAABBAB
A	heavy	Mus.musculus	Mo_IGHV5-9*01	97.3	Mo_IGHV5-9*01	100.0	H4	8	H4-8-1	4	RDNAKNTL	BBAAALBB
C	kappa	Mus.musculus	Mo_IGKV5-43*01	95.7	Mo_IGKV5-43*01	81.8	L1	11	L1-11-1	5	RASQTISDNLH	BBABBAEABBB
C	kappa	Mus.musculus	Mo_IGKV5-43*01	95.7	Mo_IGKV5-43*01	87.5	L2	8	L2-8-1	15	KYSSQSIS	BLLABBBB
C	kappa	Mus.musculus	Mo_IGKV5-43*01	95.7	Mo_IGKV5-43*01	85.7	L3	9	L3-9-cis7-1	7	QQTNSWPLT	BBAABBbBB
C	kappa	Mus.musculus	Mo_IGKV5-43*01	95.7	Mo_IGKV5-43*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB
H	heavy	Mus.musculus	Mo_IGHV5-9*01	97.3	Mo_IGHV5-9*01	53.8	H1	13	H1-13-1	10	EASGFSFGFYSLS	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV5-9*01	97.3	CDRLenMismatch	-1.0	H2	12	H2-12-1	20	TIAGSgvGGQTY	BBBBAAALLBBB
H	heavy	Mus.musculus	Mo_IGHV5-9*01	97.3	Mo_IGHV5-9*01	100.0	H3	14	H3-14-*	-1	ARHGEGKYGSNFAY	BBBBBEABAABBAB
H	heavy	Mus.musculus	Mo_IGHV5-9*01	97.3	Mo_IGHV5-9*01	100.0	H4	8	H4-8-1	4	RDNAKNTL	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV5-43*01	95.7	Mo_IGKV5-43*01	81.8	L1	11	L1-11-1	5	RASQTISDNLH	BBABBAEABBB
L	kappa	Mus.musculus	Mo_IGKV5-43*01	95.7	Mo_IGKV5-43*01	87.5	L2	8	L2-8-1	15	KYSSQSIS	BLLABBBB
L	kappa	Mus.musculus	Mo_IGKV5-43*01	95.7	Mo_IGKV5-43*01	85.7	L3	9	L3-9-cis7-1	7	QQTNSWPLT	BBAABBbBB
L	kappa	Mus.musculus	Mo_IGKV5-43*01	95.7	Mo_IGKV5-43*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022