PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6WFZ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-49*03	94.5	Hu_IGHV3-49*03	92.3	H1	13	H1-13-1	8	TTSGFTFGDYAMS	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-49*03	94.5	Hu_IGHV3-49*03	75.0	H2	12	H2-12-1	15	FIRSKgfGGTAE	BBBBAAALLBBB
A	heavy	Homo.sapiens	Hu_IGHV3-49*03	94.5	Hu_IGHV3-49*03	50.0	H3	12	H3-12-*	-1	SRVGVVIATAVY	BBBBAABBBBAB
A	heavy	Homo.sapiens	Hu_IGHV3-49*03	94.5	Hu_IGHV3-49*03	87.5	H4	8	H4-8-1	4	RDDSRSIA	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV2D-29*02	95.7	Hu_IGKV2D-29*02	87.5	L1	16	L1-16-1	5	KSSQSLldndgKTYLY	BBABBABBAALBBBBB
B	kappa	Homo.sapiens	Hu_IGKV2D-29*02	95.7	Hu_IGKV2D-29*02	100.0	L2	8	L2-8-1	7	YEVSNRFS	BLEABBBB
B	kappa	Homo.sapiens	Hu_IGKV2D-29*02	95.7	Hu_IGKV2D-29*02	71.4	L3	9	L3-9-cis7-1	8	MQRIDLPWT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV2D-29*02	95.7	Hu_IGKV2D-29*02	100.0	L4	6	L4-6-1	5	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-49*03	94.5	Hu_IGHV3-49*03	92.3	H1	13	H1-13-1	8	TTSGFTFGDYAMS	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-49*03	94.5	Hu_IGHV3-49*03	75.0	H2	12	H2-12-1	15	FIRSKgfGGTAE	BBBBAAALLBBB
H	heavy	Homo.sapiens	Hu_IGHV3-49*03	94.5	Hu_IGHV3-49*03	50.0	H3	12	H3-12-*	-1	SRVGVVIATAVY	BBBBAABBBBAB
H	heavy	Homo.sapiens	Hu_IGHV3-49*03	94.5	Hu_IGHV3-49*03	87.5	H4	8	H4-8-1	3	RDDSRSIA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV2D-29*02	95.7	Hu_IGKV2D-29*02	87.5	L1	16	L1-16-1	8	KSSQSLldndgKTYLY	BBABBABBAALBBBBB
L	kappa	Homo.sapiens	Hu_IGKV2D-29*02	95.7	Hu_IGKV2D-29*02	100.0	L2	8	L2-8-1	7	YEVSNRFS	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV2D-29*02	95.7	Hu_IGKV2D-29*02	71.4	L3	9	L3-9-cis7-1	7	MQRIDLPWT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV2D-29*02	95.7	Hu_IGKV2D-29*02	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022