PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6VY4

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	heavy	Homo.sapiens	Hu_IGHV1-69*08	89.0	Hu_IGHV1-69*08	53.8	H1	13	H1-13-*	-1	KVSGGIFNRETIN	BBBEEBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV1-69*08	89.0	Hu_IGHV1-69*08	50.0	H2	10	H2-10-1	21	RITPIVDVPN	BBBAAALBBB
C	heavy	Homo.sapiens	Hu_IGHV1-69*08	89.0	Hu_IGHV1-69*08	100.0	H3	11	H3-11-*	-1	ARFRGHNYFDP	BBBBLLABBBb
C	heavy	Homo.sapiens	Hu_IGHV1-69*08	89.0	Hu_IGHV1-69*08	87.5	H4	8	H4-8-1	5	ADKSTSTV	BBAAALBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	94.0	Hu_IGLV3-21*02	90.9	L1	11	L1-11-3	4	GGNNIGGKSVH	BBBLAAABBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	94.0	Hu_IGLV3-21*02	87.5	L2	8	L2-8-1	9	YDDRDRPS	BLLABBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	94.0	Hu_IGLV3-21*02	66.7	L3	11	L3-11-1	10	QVWDNASDEAV	BBBBAAALBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	94.0	Hu_IGLV3-21*02	83.3	L4	6	L4-6-2	14	NSGDTA	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	89.0	Hu_IGHV1-69*08	53.8	H1	13	H1-13-1	16	KVSGGIFNRETIN	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	89.0	Hu_IGHV1-69*08	50.0	H2	10	H2-10-1	22	RITPIVDVPN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	89.0	Hu_IGHV1-69*08	100.0	H3	11	H3-11-*	-1	ARFRGHNYFDP	BBBBLLABBBb
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	89.0	Hu_IGHV1-69*08	87.5	H4	8	H4-8-1	8	ADKSTSTV	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-21*02	94.0	Hu_IGLV3-21*02	90.9	L1	11	L1-11-3	5	GGNNIGGKSVH	BBBLAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-21*02	94.0	Hu_IGLV3-21*02	87.5	L2	8	L2-8-1	10	YDDRDRPS	BLLABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-21*02	94.0	Hu_IGLV3-21*02	66.7	L3	11	L3-11-1	9	QVWDNASDEAV	BBBBAAALBBB
L	lambda	Homo.sapiens	Hu_IGLV3-21*02	94.0	Hu_IGLV3-21*02	83.3	L4	6	L4-6-2	14	NSGDTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022