PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6UUM

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV3D-20*02	82.6	Hu_IGKV3D-20*02	66.7	L1	12	L1-12-1	7	RASQNISsSWIA	BBABBBBAAABB
A	kappa	Homo.sapiens	Hu_IGKV3D-20*02	82.6	Hu_IGKV3D-20*02	50.0	L2	8	L2-8-1	6	SAASARAA	BLLABBBB
A	kappa	Homo.sapiens	Hu_IGKV3D-20*02	82.6	Hu_IGKV3D-20*02	14.3	L3	9	L3-9-*	-1	QYYGGSFFT	BBABEABBB
A	kappa	Homo.sapiens	Hu_IGKV3D-20*02	82.6	Hu_IGKV3D-20*02	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV1-69*17	67.1	Hu_IGHV1-69*17	53.8	H1	13	H1-13-*	-1	KPVGGTFTNFAIH	BBBLEBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV1-69*17	67.1	Hu_IGHV1-69*17	40.0	H2	10	H2-10-3	16	GRVPVVGIYK	BBBBLALBBB
B	heavy	Homo.sapiens	Hu_IGHV1-69*17	67.1	Hu_IGHV1-69*17	50.0	H3	23	H3-23-*	-1	TRwrgagmapydtSSYYNDASDV
B	heavy	Homo.sapiens	Hu_IGHV1-69*17	67.1	Hu_IGHV1-69*17	25.0	H4	8	H4-8-1	8	EDDPMKTV	BBAAALBB
F	kappa	Homo.sapiens	Hu_IGKV3D-20*02	82.6	Hu_IGKV3D-20*02	66.7	L1	12	L1-12-1	7	RASQNISsSWIA	BBABBBBAAABB
F	kappa	Homo.sapiens	Hu_IGKV3D-20*02	82.6	Hu_IGKV3D-20*02	50.0	L2	8	L2-8-1	6	SAASARAA	BLLABBBB
F	kappa	Homo.sapiens	Hu_IGKV3D-20*02	82.6	Hu_IGKV3D-20*02	14.3	L3	9	L3-9-*	-1	QYYGGSFFT	BBABEABBB
F	kappa	Homo.sapiens	Hu_IGKV3D-20*02	82.6	Hu_IGKV3D-20*02	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-69*17	67.1	Hu_IGHV1-69*17	53.8	H1	13	H1-13-*	-1	KPVGGTFTNFAIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*17	67.1	Hu_IGHV1-69*17	40.0	H2	10	H2-10-3	14	GRVPVVGIYK	BBBBEALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*17	67.1	Hu_IGHV1-69*17	50.0	H3	23	H3-23-*	-1	TRwrgagmapyDTSSYYNDASDV
H	heavy	Homo.sapiens	Hu_IGHV1-69*17	67.1	Hu_IGHV1-69*17	25.0	H4	8	H4-8-1	9	EDDPMKTV	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022