PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6UUL

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV1-69*17	68.5	Hu_IGHV1-69*17	53.8	H1	13	H1-13-*	-1	KPVGGTFTNFAIH	BBBEEBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV1-69*17	68.5	Hu_IGHV1-69*17	40.0	H2	10	H2-10-3	13	GRVPVVGIYK	BBBBEALBBB
A	heavy	Homo.sapiens	Hu_IGHV1-69*17	68.5	Hu_IGHV1-69*17	50.0	H3	23	H3-23-*	-1	TRwrgcgmcpyDTSSYYNDASDV
A	heavy	Homo.sapiens	Hu_IGHV1-69*17	68.5	Hu_IGHV1-69*17	25.0	H4	8	H4-8-1	11	EDDPMKTV	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV3D-20*02	81.2	Hu_IGKV3D-20*02	66.7	L1	12	L1-12-1	8	RASQNISsSWIA	BBABBBBAAABB
B	kappa	Homo.sapiens	Hu_IGKV3D-20*02	81.2	Hu_IGKV3D-20*02	50.0	L2	8	L2-8-1	6	SAASARAA	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV3D-20*02	81.2	Hu_IGKV3D-20*02	14.3	L3	9	L3-9-*	-1	QYYGGSFFT	BBABEABBB
B	kappa	Homo.sapiens	Hu_IGKV3D-20*02	81.2	Hu_IGKV3D-20*02	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB
C	heavy	Homo.sapiens	Hu_IGHV1-69*17	68.5	Hu_IGHV1-69*17	53.8	H1	13	H1-13-4	25	KPVGGTFTNFAIH	BBBLBBABLBBBB
C	heavy	Homo.sapiens	Hu_IGHV1-69*17	68.5	Hu_IGHV1-69*17	40.0	H2	10	H2-10-*	-1	GRVPVVGIYK	BBBABBLBBB
C	heavy	Homo.sapiens	Hu_IGHV1-69*17	68.5	Hu_IGHV1-69*17	50.0	H3	23	H3-23-*	-1	TRwrgcgmcpydtssyynDASDV
C	heavy	Homo.sapiens	Hu_IGHV1-69*17	68.5	Hu_IGHV1-69*17	25.0	H4	8	H4-8-1	10	EDDPMKTV	BBAAALBB
D	kappa	Homo.sapiens	Hu_IGKV3D-20*02	81.2	Hu_IGKV3D-20*02	66.7	L1	12	L1-12-1	9	RASQNISsSWIA	BBABBBBAAABB
D	kappa	Homo.sapiens	Hu_IGKV3D-20*02	81.2	Hu_IGKV3D-20*02	50.0	L2	8	L2-8-1	5	SAASARAA	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV3D-20*02	81.2	Hu_IGKV3D-20*02	14.3	L3	9	L3-9-3	21	QYYGGSFFT	BBBBAABBB
D	kappa	Homo.sapiens	Hu_IGKV3D-20*02	81.2	Hu_IGKV3D-20*02	100.0	L4	6	L4-6-2	14	GSGTDF	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022