PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6S8I

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	84.6	H1	13	H1-13-1	16	AASGFTFSDAWMT	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	66.7	H2	12	H2-12-1	11	RIKSNadGGATE	BBBBAAALLBBB
H	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	50.0	H3	8	H3-8-*	-1	LTPPPRRY	BBBBbLAL
H	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	62.5	H4	8	H4-8-1	9	RDDSRSSL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	92.9	L1	14	L1-14-3	13	TGSYSNIGAgYDVH	BBBAAAAAALBBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	50.0	L2	8	L2-8-*	-1	YAYTNRPA	ABAABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	55.6	L3	12	L3-12-*	-1	QSYDARLRdGEV
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	83.3	L4	6	L4-6-2	12	KSGSSA	BBEABB
O	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	92.9	L1	14	L1-14-3	13	TGSYSNIGAgYDVH	BBBAAAAAALBBBB
O	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	50.0	L2	8	L2-8-*	-1	YAYTNRPA	ABAABBBB
O	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	55.6	L3	12	L3-12-*	-1	QSYDARLRdGEV
O	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	83.3	L4	6	L4-6-2	12	KSGSSA	BBEABB
P	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	84.6	H1	13	H1-13-1	16	AASGFTFSDAWMT	BBBLBBAAABBBB
P	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	66.7	H2	12	H2-12-1	11	RIKSNadGGATE	BBBBAAALLBBB
P	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	50.0	H3	8	H3-8-*	-1	LTPPPRRY	BBBBbLAL
P	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	62.5	H4	8	H4-8-1	9	RDDSRSSL	BBAAALBB
U	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	92.9	L1	14	L1-14-3	13	TGSYSNIGAgYDVH	BBBAAAAAALBBBB
U	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	50.0	L2	8	L2-8-*	-1	YAYTNRPA	ABAABBBB
U	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	55.6	L3	12	L3-12-*	-1	QSYDARLRdGEV
U	lambda	Homo.sapiens	Hu_IGLV1-40*01	89.7	Hu_IGLV1-40*01	83.3	L4	6	L4-6-2	12	KSGSSA	BBEABB
Y	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	84.6	H1	13	H1-13-1	16	AASGFTFSDAWMT	BBBLBBAAABBBB
Y	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	66.7	H2	12	H2-12-1	11	RIKSNadGGATE	BBBBAAALLBBB
Y	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	50.0	H3	8	H3-8-*	-1	LTPPPRRY	BBBBbLAL
Y	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	62.5	H4	8	H4-8-1	9	RDDSRSSL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022