PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6PZZ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
E	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	100.0	L1	11	L1-11-1	24	RASQSISSYLN	BBABBAEABBB
E	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	100.0	L2	8	L2-8-1	7	YAASSLQS	BLEABBBB
E	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	85.7	L3	9	L3-9-cis7-1	15	QQSYSAPFT	BBAABBbBB
E	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	11	ASGTDF	BBEABB
F	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	92.3	H1	13	H1-13-1	7	KASGYTFISYGIS	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H2	10	H2-10-*	-1	WISAYNGNTN	BBBAAALAEB
F	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H3	14	H3-14-*	-1	ARVIPGTAVDYFDY	BBBABAABBBEBAB
F	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H4	8	H4-8-1	10	TDTSTSTA	BBAAALBB
G	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	100.0	L1	11	L1-11-1	24	RASQSISSYLN	BBABBAEABBB
G	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	100.0	L2	8	L2-8-1	7	YAASSLQS	BLEABBBB
G	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	85.7	L3	9	L3-9-cis7-1	15	QQSYSAPFT	BBAABBbBB
G	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	11	ASGTDF	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	92.3	H1	13	H1-13-1	7	KASGYTFISYGIS	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H2	10	H2-10-*	-1	WISAYNGNTN	BBBAAALAEB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H3	14	H3-14-*	-1	ARVIPGTAVDYFDY	BBBABAABBBEBAB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H4	8	H4-8-1	10	TDTSTSTA	BBAAALBB
I	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	92.3	H1	13	H1-13-1	7	KASGYTFISYGIS	BBBLBBAAABBBB
I	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H2	10	H2-10-*	-1	WISAYNGNTN	BBBAAALAEB
I	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H3	14	H3-14-*	-1	ARVIPGTAVDYFDY	BBBABAABBBEBAB
I	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H4	8	H4-8-1	10	TDTSTSTA	BBAAALBB
J	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	100.0	L1	11	L1-11-1	24	RASQSISSYLN	BBABBAEABBB
J	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	100.0	L2	8	L2-8-1	7	YAASSLQS	BLEABBBB
J	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	85.7	L3	9	L3-9-cis7-1	15	QQSYSAPFT	BBAABBbBB
J	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	11	ASGTDF	BBEABB
K	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	92.3	H1	13	H1-13-1	7	KASGYTFISYGIS	BBBLBBAAABBBB
K	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H2	10	H2-10-*	-1	WISAYNGNTN	BBBAAALAEB
K	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H3	14	H3-14-*	-1	ARVIPGTAVDYFDY	BBBABAABBBEBAB
K	heavy	Homo.sapiens	Hu_IGHV1-18*01	97.3	Hu_IGHV1-18*01	100.0	H4	8	H4-8-1	10	TDTSTSTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	100.0	L1	11	L1-11-1	24	RASQSISSYLN	BBABBAEABBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	100.0	L2	8	L2-8-1	7	YAASSLQS	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	85.7	L3	9	L3-9-cis7-1	16	QQSYSAPFT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	95.7	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	11	ASGTDF	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022