PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6PWC

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Synthetic.construct	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	53.8	H1	13	H1-13-1	17	AASGFNVYSSSIH	BBBLBBAAABBBB
H	heavy	Synthetic.construct	Hu_IGHV3-66*01	94.5	CDRLenMismatch	-1.0	H2	10	H2-10-1	18	SISSYYCYTY	BBBAAALBBB
H	heavy	Synthetic.construct	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	13	H3-13-*	-1	ARSRQFWYSGLDY	BBBBAABBAEBAB
H	heavy	Synthetic.construct	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	15	ADTSKNTA	BBAAALBB
L	kappa	Synthetic.construct	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BBABBBAABBB
L	kappa	Synthetic.construct	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	75.0	L2	8	L2-8-1	13	YSASSLYS	BLLABBBB
L	kappa	Synthetic.construct	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	42.9	L3	9	L3-9-cis7-1	15	QQYKYVPVT	BBAABBbBB
L	kappa	Synthetic.construct	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	11	RSGTDF	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022