PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6PEH

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	64.3	H1	14	H1-14-*	-1	TASGFSFGwNDYMS	BBBLBBBBAABBBB
A	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	81.8	H2	11	H2-11-*	-1	CIYAGsTRSTY	BBBABAALBBB
A	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	100.0	H3	20	H3-20-*	-1	ARGAVTYdglggaYLKHFNL
A	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	85.7	H4	7	H4-7-1	11	KTSSTAV	BABAABB
B	kappa	Homo.sapiens	Rb_IGKV1S47*01	95.6	Rb_IGKV1S47*01	81.8	L1	11	L1-11-1	8	RASEDIESYLA	BBABBAEABBB
B	kappa	Homo.sapiens	Rb_IGKV1S47*01	95.6	Rb_IGKV1S47*01	62.5	L2	8	L2-8-1	10	YDTSKLAS	BLLABBBB
B	kappa	Homo.sapiens	Rb_IGKV1S47*01	95.6	Rb_IGKV1S47*01	11.1	L3	13	L3-13-*	-1	LygyiSSDRIDFG	BBBBBBAABBBBB
B	kappa	Homo.sapiens	Rb_IGKV1S47*01	95.6	Rb_IGKV1S47*01	100.0	L4	6	L4-6-1	9	GSGTQF	EBEABB
H	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	64.3	H1	14	H1-14-*	-1	TASGFSFGwNDYMS	BBBLBBBBAABBBB
H	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	81.8	H2	11	H2-11-*	-1	CIYAGstrSTY
H	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	100.0	H3	20	H3-20-*	-1	ARGAVTYdglggaYLKHFNL
H	heavy	Homo.sapiens	Rb_IGHV1S40*01	94.3	Rb_IGHV1S40*01	85.7	H4	7	H4-7-1	13	KTSSTAV	BABAABB
L	kappa	Homo.sapiens	Rb_IGKV1S47*01	95.6	Rb_IGKV1S47*01	81.8	L1	11	L1-11-1	12	RASEDIESYLA	BBABBAEABBB
L	kappa	Homo.sapiens	Rb_IGKV1S47*01	95.6	Rb_IGKV1S47*01	62.5	L2	8	L2-8-1	11	YDTSKLAS	BLLABBBB
L	kappa	Homo.sapiens	Rb_IGKV1S47*01	95.6	Rb_IGKV1S47*01	11.1	L3	13	L3-13-*	-1	LygyiSSDRIDFG	BBBBBBAABBBBB
L	kappa	Homo.sapiens	Rb_IGKV1S47*01	95.6	Rb_IGKV1S47*01	100.0	L4	6	L4-6-1	12	GSGTQF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022