PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6OT1

#CDRs = 8; #Clusters = 21.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	90.4	CDRLenMismatch	-1.0	H1	15	H1-15-1	26	GVSGGTISSshFYWS	BBBLEBAABBLBBBB
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	90.4	Ma_IGHV4-2*01	0.0	H2	10	H2-10-1	20	GLYINDERIN	BBBAAALBBB
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	90.4	Ma_IGHV4-2*01	50.0	H3	14	H3-14-*	-1	VREPVIAAAGTVDV	BBBBABAAAEABBB
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	90.4	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	14	KDTSQNQF	BBAAALBB
C	kappa	Macaca.mulatta	Ma_IGKV2S17*01	95.7	CDRLenMismatch	-1.0	L1	16	L1-16-1	14	RSSQSLlhsngHTYVH	BBABBABBAALBBBBB
C	kappa	Macaca.mulatta	Ma_IGKV2S17*01	95.7	Ma_IGKV2S17*01	100.0	L2	8	L2-8-*	-1	YEVSNRAS	BLBLBBBA
C	kappa	Macaca.mulatta	Ma_IGKV2S17*01	95.7	Ma_IGKV2S17*01	42.9	L3	9	L3-9-cis7-1	13	EQTLQIPFT	BBAABBbBB
C	kappa	Macaca.mulatta	Ma_IGKV2S17*01	95.7	Ma_IGKV2S17*01	83.3	L4	6	L4-6-*	-1	GSGTDF	EBBLBB
F	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBAB
F	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
F	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	14	LDKSKNLV	BBAAALBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	90.4	CDRLenMismatch	-1.0	H1	15	H1-15-1	26	GVSGGTISSshFYWS	BBBLEBAABBLBBBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	90.4	Ma_IGHV4-2*01	0.0	H2	10	H2-10-1	20	GLYINDERIN	BBBAAALBBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	90.4	Ma_IGHV4-2*01	50.0	H3	14	H3-14-*	-1	VREPVIAAAGTVDV	BBBBABAAAEABBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	90.4	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	14	KDTSQNQF	BBAAALBB
I	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
I	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
I	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
I	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
J	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	15	RASGYNFRDYSIH	BBBLBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	21	WIKPLWGAVS	BBBAAALBBB
J	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
J	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	22	YDTSRRAS	BLLABBBB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-*	-1	QQFEF	BBLAB
K	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	17	GSGTDF	EBEABB
L	kappa	Macaca.mulatta	Ma_IGKV2S17*01	95.7	CDRLenMismatch	-1.0	L1	16	L1-16-1	14	RSSQSLlhsngHTYVH	BBABBABBAALBBBBB
L	kappa	Macaca.mulatta	Ma_IGKV2S17*01	95.7	Ma_IGKV2S17*01	100.0	L2	8	L2-8-*	-1	YEVSNRAS	BLBLBBBA
L	kappa	Macaca.mulatta	Ma_IGKV2S17*01	95.7	Ma_IGKV2S17*01	42.9	L3	9	L3-9-cis7-1	13	EQTLQIPFT	BBAABBbBB
L	kappa	Macaca.mulatta	Ma_IGKV2S17*01	95.7	Ma_IGKV2S17*01	83.3	L4	6	L4-6-*	-1	GSGTDF	EBBLBB
M	heavy	Macaca.mulatta	Hu_IGHV4-59*02	79.5	CDRLenMismatch	-1.0	H1	15	H1-15-1	26	GVSGGTISSshFYWS	BBBLEBAABBLBBBB
M	heavy	Macaca.mulatta	Hu_IGHV4-59*02	79.5	Ma_IGHV4-2*01	0.0	H2	10	H2-10-1	20	GLYINDERIN	BBBAAALBBB
M	heavy	Macaca.mulatta	Hu_IGHV4-59*02	79.5	Ma_IGHV4-2*01	50.0	H3	14	H3-14-*	-1	VREPVIAAAGTVDV	BBBBABAAAEABBB
M	heavy	Macaca.mulatta	Hu_IGHV4-59*02	79.5	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	14	KDTSQNQF	BBAAALBB
N	kappa	Macaca.mulatta	Hu_IGLV3-21*02	76.9	CDRLenMismatch	-1.0	L1	16	L1-16-1	14	RSSQSLlhsngHTYVH	BBABBABBAALBBBBB
N	kappa	Macaca.mulatta	Hu_IGLV3-21*02	76.9	Ma_IGKV2S17*01	100.0	L2	8	L2-8-*	-1	YEVSNRAS	BLBLBBBA
N	kappa	Macaca.mulatta	Hu_IGLV3-21*02	76.9	Ma_IGKV2S17*01	42.9	L3	9	L3-9-cis7-1	13	EQTLQIPFT	BBAABBbBB
N	kappa	Macaca.mulatta	Hu_IGLV3-21*02	76.9	Ma_IGKV2S17*01	83.3	L4	6	L4-6-*	-1	GSGTDF	EBBLBB
Q	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
Q	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBAB
Q	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
Q	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	14	LDKSKNLV	BBAAALBB
R	lambda	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
R	lambda	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
R	lambda	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
R	lambda	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
S	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	15	RASGYNFRDYSIH	BBBLBBAAABBBB
S	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	21	WIKPLWGAVS	BBBAAALBBB
S	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
S	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
T	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
T	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	22	YDTSRRAS	BLLABBBB
T	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-*	-1	QQFEF	BBLAB
T	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	17	GSGTDF	EBEABB
m	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
m	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBAB
m	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
m	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	14	LDKSKNLV	BBAAALBB
n	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
n	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
n	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
n	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
q	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	15	RASGYNFRDYSIH	BBBLBBAAABBBB
q	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	21	WIKPLWGAVS	BBBAAALBBB
q	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
q	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
r	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
r	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	22	YDTSRRAS	BLLABBBB
r	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-*	-1	QQFEF	BBLAB
r	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	17	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022