PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6OSY

#CDRs = 8; #Clusters = 21.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
5	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
5	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBBB
5	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
5	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	18	LDKSKNLV	BBAAALBB
6	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
6	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
6	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
6	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
7	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
7	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	22	YDTSRRAS	BLLABBBB
7	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-1	41	QQFEF	BBAAB
7	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
8	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	15	RASGYNFRDYSIH	BBBLBBAAABBBB
8	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	17	WIKPLWGAVS	BBBAAALBBB
8	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
8	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
C	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBBB
C	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
C	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	17	LDKSKNLV	BBAAALBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
E	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
E	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	23	YDTSRRAS	BLLABBBB
E	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-1	40	QQFEF	BBAAB
E	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
F	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	15	RASGYNFRDYSIH	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	17	WIKPLWGAVS	BBBAAALBBB
F	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
F	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
H	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	53.3	H1	15	H1-15-1	30	AVSGDTISSpyYFWS	BBBLBBAABBLBBBB
H	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	None	-1.0	H2	10	H2-10-*	-1	GLYSNTMDVY	BBBAABABBB
H	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	100.0	H3	15	H3-15-*	-1	ARERVVAhNYYGLDL
H	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	87.5	H4	8	H4-8-1	24	RDTSKNHF	BBAAALBB
I	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	53.3	H1	15	H1-15-1	30	AVSGDTISSpyYFWS	BBBLBBAABBLBBBB
I	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	None	-1.0	H2	10	H2-10-*	-1	GLYSNTMDVY	BBBAABABBB
I	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	100.0	H3	15	H3-15-*	-1	ARERVVAhNYYGLDL
I	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	87.5	H4	8	H4-8-1	24	RDTSKNHF	BBAAALBB
J	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	63.6	L1	11	L1-11-1	28	RASQDIKNSLS	BBABBALABBB
J	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	50.0	L2	8	L2-8-1	24	HHSSTLET	BLLABBBB
J	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	57.1	L3	9	L3-9-cis7-1	10	QQYEDFPLT	BBAABBbBB
J	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	66.7	L4	6	L4-6-1	18	GYGTEF	EBEABB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	63.6	L1	11	L1-11-*	-1	RASQDIKNSLS	BBABBALABBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	50.0	L2	8	L2-8-1	22	HHSSTLET	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	57.1	L3	9	L3-9-cis7-1	10	QQYEDFPLT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	66.7	L4	6	L4-6-1	17	GYGTEF	EBEABB
M	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
M	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBAB
M	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
M	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	18	LDKSKNLV	BBAAALBB
N	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
N	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
N	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
N	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
O	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
O	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	22	YDTSRRAS	BLLABBBB
O	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-1	41	QQFEF	BBAAB
O	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
P	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	16	RASGYNFRDYSIH	BBBLBBAAABBBB
P	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	17	WIKPLWGAVS	BBBAAALBBB
P	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
P	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
R	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	53.3	H1	15	H1-15-1	30	AVSGDTISSpyYFWS	BBBLBBAABBLBBBB
R	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	None	-1.0	H2	10	H2-10-*	-1	GLYSNTMDVY	BBBABBABBB
R	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	100.0	H3	15	H3-15-*	-1	ARERVVAhNYYGLDL
R	heavy	Homo.sapiens	Hu_IGHV4-61*03	82.2	Hu_IGHV4-61*03	87.5	H4	8	H4-8-1	23	RDTSKNHF	BBAAALBB
S	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	63.6	L1	11	L1-11-1	28	RASQDIKNSLS	BBABBALABBB
S	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	50.0	L2	8	L2-8-1	23	HHSSTLET	BLLABBBB
S	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	57.1	L3	9	L3-9-cis7-1	9	QQYEDFPLT	BBAABBbBB
S	kappa	Homo.sapiens	Hu_IGKV1-33*01	85.5	Hu_IGKV1-33*01	66.7	L4	6	L4-6-1	17	GYGTEF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022