PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6NFC

#CDRs = 8; #Clusters = 14.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	53.8	H1	13	H1-13-1	21	RASGYTFSSFAMS	BBBEBBAAABBBB
C	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	50.0	H2	10	H2-10-2	11	LINDRGGLTF	BBBAALABBB
C	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	33.3	H3	18	H3-18-*	-1	ATGGMssalQSSKYYFDF
C	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	62.5	H4	8	H4-8-1	11	RDNSKNTL	BBAAALBB
D	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	92.9	L1	14	L1-14-*	-1	TGTSSDIGSyNYVS	BBAAAAAAABABBB
D	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	75.0	L2	8	L2-8-4	15	YDVTQRPS	BEAABBBB
D	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	66.7	L3	11	L3-11-*	-1	SAYAGRQTFYI	BBBALLAAEBB
D	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	100.0	L4	6	L4-6-2	9	KSGNTA	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-2*02	100.0	Hu_IGHV1-2*02	100.0	H1	13	H1-13-4	13	KASGYTFTGYYMH	BBBLBBABLBBBB
H	heavy	Homo.sapiens	Hu_IGHV1-2*02	100.0	Hu_IGHV1-2*02	100.0	H2	10	H2-10-1	11	WINPNSGGTN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-2*02	100.0	Hu_IGHV1-2*02	100.0	H3	21	H3-21-*	-1	ARDRgreweleSYYYYYYMDV
H	heavy	Homo.sapiens	Hu_IGHV1-2*02	100.0	Hu_IGHV1-2*02	100.0	H4	8	H4-8-1	11	RDTSISTA	BBAAALBB
J	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	53.8	H1	13	H1-13-1	21	RASGYTFSSFAMS	BBBEBBAAABBBB
J	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	50.0	H2	10	H2-10-2	11	LINDRGGLTF	BBBAALABBB
J	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	33.3	H3	18	H3-18-*	-1	ATGGMssalQSSKYYFDF
J	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	62.5	H4	8	H4-8-1	10	RDNSKNTL	BBAAALBB
K	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	53.8	H1	13	H1-13-1	20	RASGYTFSSFAMS	BBBEBBAAABBBB
K	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	50.0	H2	10	H2-10-2	10	LINDRGGLTF	BBBAALABBB
K	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	33.3	H3	18	H3-18-*	-1	ATGGMssalQSSKYYFDF
K	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	62.5	H4	8	H4-8-1	11	RDNSKNTL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L1	11	L1-11-4	10	SGDALPKQYAY	BEAAAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L2	8	L2-8-*	-1	YKDSERPS	BLEABBBE
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L3	11	L3-11-2	11	QSADSSGTYVV	BBBBAALABBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L4	6	L4-6-2	10	SSGTTV	BBEABB
M	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	92.9	L1	14	L1-14-*	-1	TGTSSDIGSyNYVS	BBAAAAAAABBBBB
M	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	75.0	L2	8	L2-8-4	14	YDVTQRPS	BEAABBBB
M	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	66.7	L3	11	L3-11-*	-1	SAYAGRQTFYI	BBBALLAAEBB
M	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	100.0	L4	6	L4-6-2	9	KSGNTA	BBEABB
N	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	92.9	L1	14	L1-14-*	-1	TGTSSDIGSyNYVS	BBAAAAAAABBBBB
N	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	75.0	L2	8	L2-8-4	14	YDVTQRPS	BEAABBBB
N	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	66.7	L3	11	L3-11-*	-1	SAYAGRQTFYI	BBBALLAAEBB
N	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	100.0	L4	6	L4-6-2	9	KSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022