PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6NF5

#CDRs = 8; #Clusters = 14.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
E	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H1	15	H1-15-*	-1	TVSGGSISsgSYYWS	BBBLBBBABEABBBB
E	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H2	9	H2-9-1	9	RIYTSGSTN	BBBAALBBB
E	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H3	23	H3-23-*	-1	AREGftifgvvtfSEGYYYGMDV
E	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H4	8	H4-8-1	16	VDTSKNQF	BBAAALBB
F	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L1	11	L1-11-4	11	SGDALPKQYAY	BEAAAAABBBB
F	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L2	8	L2-8-*	-1	YKDSERPS	BLLLBBBB
F	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	77.8	L3	9	L3-9-*	-1	QSADssgeV
F	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L4	6	L4-6-2	9	SSGTTV	BBEABB
G	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	53.8	H1	13	H1-13-1	14	RASGYTFSSFAMS	BBBLBBAAABBBB
G	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	50.0	H2	10	H2-10-2	11	LINDRGGLTF	BBBAALABBB
G	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	33.3	H3	18	H3-18-*	-1	ATGGMssalQSSKYYFDF
G	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	62.5	H4	8	H4-8-1	10	RDNSKNTL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H1	15	H1-15-*	-1	TVSGGSISsgSYYWS	BBBLBBBABEABBBB
H	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H2	9	H2-9-1	9	RIYTSGSTN	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H3	23	H3-23-*	-1	AREGftifgvvtfSEGYYYGMDV
H	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H4	8	H4-8-1	16	VDTSKNQF	BBAAALBB
I	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	92.9	L1	14	L1-14-*	-1	TGTSSDIGSyNYVS	BBAAAAAAABBBBB
I	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	75.0	L2	8	L2-8-4	17	YDVTQRPS	BEAABBBB
I	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	66.7	L3	11	L3-11-*	-1	SAYAGRQTFYI	BBBALLAAEBB
I	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	100.0	L4	6	L4-6-2	9	KSGNTA	BBEABB
K	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	53.8	H1	13	H1-13-1	14	RASGYTFSSFAMS	BBBLBBAAABBBB
K	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	50.0	H2	10	H2-10-2	11	LINDRGGLTF	BBBAALABBB
K	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	33.3	H3	18	H3-18-*	-1	ATGGMssalQSSKYYFDF
K	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	62.5	H4	8	H4-8-1	10	RDNSKNTL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L1	11	L1-11-4	11	SGDALPKQYAY	BEAAAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L2	8	L2-8-*	-1	YKDSERPS	BLLLBBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	77.8	L3	9	L3-9-*	-1	QSADssgeV
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L4	6	L4-6-2	9	SSGTTV	BBEABB
N	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	92.9	L1	14	L1-14-*	-1	TGTSSDIGSyNYVS	BBAAAAAAABBBBB
N	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	75.0	L2	8	L2-8-4	17	YDVTQRPS	BEAABBBB
N	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	66.7	L3	11	L3-11-*	-1	SAYAGRQTFYI	BBBALLAAEBB
N	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	100.0	L4	6	L4-6-2	9	KSGNTA	BBEABB
O	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H1	15	H1-15-*	-1	TVSGGSISsgSYYWS	BBBLBBBABEABBBB
O	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H2	9	H2-9-1	9	RIYTSGSTN	BBBAALBBB
O	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H3	23	H3-23-*	-1	AREGftifgvvtfSEGYYYGMDV
O	heavy	Homo.sapiens	Hu_IGHV4-61*02	100.0	Hu_IGHV4-61*02	100.0	H4	8	H4-8-1	16	VDTSKNQF	BBAAALBB
P	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L1	11	L1-11-4	11	SGDALPKQYAY	BEAAAAABBBB
P	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L2	8	L2-8-*	-1	YKDSERPS	BLLLBBBB
P	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	77.8	L3	9	L3-9-*	-1	QSADssgeV
P	lambda	Homo.sapiens	Hu_IGLV3-25*02	100.0	Hu_IGLV3-25*02	100.0	L4	6	L4-6-2	9	SSGTTV	BBEABB
Q	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	53.8	H1	13	H1-13-1	14	RASGYTFSSFAMS	BBBLBBAAABBBB
Q	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	50.0	H2	10	H2-10-2	11	LINDRGGLTF	BBBAALABBB
Q	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	33.3	H3	18	H3-18-*	-1	ATGGMssalQSSKYYFDF
Q	heavy	Macaca.mulatta	Ma_IGHV3-22*01	86.3	Ma_IGHV3-22*01	62.5	H4	8	H4-8-1	10	RDNSKNTL	BBAAALBB
R	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	92.9	L1	14	L1-14-*	-1	TGTSSDIGSyNYVS	BBAAAAAAABBBBB
R	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	75.0	L2	8	L2-8-4	17	YDVTQRPS	BEAABBBB
R	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	66.7	L3	11	L3-11-*	-1	SAYAGRQTFYI	BBBALLAAEBB
R	lambda	Macaca.mulatta	Ma_IGLV2S1*01	98.5	Ma_IGLV2S1*01	100.0	L4	6	L4-6-2	9	KSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022