PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6NF2

#CDRs = 8; #Clusters = 22.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	13	RASGYNFRDYSIH	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	18	WIKPLWGAVS	BBBAAALBBB
C	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
C	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	19	YDTSRRAS	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-1	42	QQFEF	BBAAB
D	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
E	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBAB
E	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
E	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	16	LDKSKNLV	BBAAALBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
F	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
H	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	None	-1.0	H1	15	H1-15-*	-1	VVSGGTPGRgfLYWS	BBBLABABBEBBBBB
H	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	None	-1.0	H2	10	H2-10-*	-1	GTATNTDITD	BBBAABABBB
H	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	Hu_IGHV4-OR15-8*02	0.0	H3	17	H3-17-*	-1	TSRAKDYrgpSYSRIDV
H	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	Hu_IGHV4-OR15-8*02	62.5	H4	8	H4-8-1	14	KDTSRNQF	BBAAALBB
J	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBAB
J	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
J	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	16	LDKSKNLV	BBAAALBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
K	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
L	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	CDRLenMismatch	-1.0	L1	16	L1-16-1	8	RSSQSLldsdgNTCLD	BBABBABBAALBBBBB
L	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	50.0	L2	8	L2-8-*	-1	YDVSNRVS	BBAABBBB
L	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	71.4	L3	9	L3-9-cis7-1	7	MQFVEFPLT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	83.3	L4	6	L4-6-3	9	GSDTDF	EBAABB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	19	YDTSRRAS	BLLABBBB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-1	42	QQFEF	BBAAB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
N	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	13	RASGYNFRDYSIH	BBBLBBAAABBBB
N	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	18	WIKPLWGAVS	BBBAAALBBB
N	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
N	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
O	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	None	-1.0	H1	15	H1-15-*	-1	VVSGGTPGRgfLYWS	BBBLABABBEBBBBB
O	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	None	-1.0	H2	10	H2-10-*	-1	GTATNTDITD	BBBAABABBB
O	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	Hu_IGHV4-OR15-8*02	0.0	H3	17	H3-17-*	-1	TSRAKDYrgpSYSRIDV
O	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	Hu_IGHV4-OR15-8*02	62.5	H4	8	H4-8-1	14	KDTSRNQF	BBAAALBB
P	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	CDRLenMismatch	-1.0	L1	16	L1-16-1	8	RSSQSLldsdgNTCLD	BBABBABBAALBBBBB
P	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	50.0	L2	8	L2-8-*	-1	YDVSNRVS	BBAABBBB
P	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	71.4	L3	9	L3-9-cis7-1	8	MQFVEFPLT	BBAABBbBB
P	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	83.3	L4	6	L4-6-3	9	GSDTDF	EBAABB
S	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	53.8	H1	13	H1-13-*	-1	NVSGTLVRDNYWS	BBBEBBAAABBBB
S	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	55.6	H2	9	H2-9-*	-1	YVHDSGDTN	BBBBLLBAB
S	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H3	26	H3-26-*	-1	ATTKHGRriygvvafkewfTYFYMDV
S	heavy	Homo.sapiens	Hu_IGHV4-59*02	79.5	Hu_IGHV4-59*02	50.0	H4	8	H4-8-1	16	LDKSKNLV	BBAAALBB
T	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	45.5	L1	11	L1-11-*	-1	GEESLGSRSVI	EBBBABBBBBB
T	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	62.5	L2	8	L2-8-*	-1	YNNNDRPS	ABAABBBB
T	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	33.3	L3	12	L3-12-*	-1	HIWDSRRpTNWV
T	lambda	Homo.sapiens	Hu_IGLV3-21*02	76.9	Hu_IGLV3-21*02	0.0	L4	9	L4-9-*	-1	pgsTFGTTA
U	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	40.0	L1	10	L1-10-*	-1	KASQGGNAMT	BBABBLBBBB
U	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Ra_IGKV4S10*01	75.0	L2	8	L2-8-1	19	YDTSRRAS	BLLABBBB
U	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	0.0	L3	5	L3-5-1	42	QQFEF	BBAAB
U	kappa	Homo.sapiens	Hu_IGKV3-20*01	79.7	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
V	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	69.2	H1	13	H1-13-1	13	RASGYNFRDYSIH	BBBLBBAAABBBB
V	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Ra_IGHV1-38*01	30.0	H2	10	H2-10-1	18	WIKPLWGAVS	BBBAAALBBB
V	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	50.0	H3	16	H3-16-*	-1	VRRGSCDYCGDFpwQY
V	heavy	Homo.sapiens	Hu_IGHV1-18*03	71.1	Hu_IGHV1-18*03	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgVA
W	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	None	-1.0	H1	15	H1-15-*	-1	VVSGGTPGRgfLYWS	BBBLABABBEBBBBB
W	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	None	-1.0	H2	10	H2-10-*	-1	GTATNTDITD	BBBAABABBB
W	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	Hu_IGHV4-OR15-8*02	0.0	H3	17	H3-17-*	-1	TSRAKDYrgpSYSRIDV
W	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	82.2	Hu_IGHV4-OR15-8*02	62.5	H4	8	H4-8-1	14	KDTSRNQF	BBAAALBB
X	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	CDRLenMismatch	-1.0	L1	16	L1-16-1	8	RSSQSLldsdgNTCLD	BBABBABBAALBBBBB
X	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	50.0	L2	8	L2-8-*	-1	YDVSNRVS	BBAABBBB
X	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	71.4	L3	9	L3-9-cis7-1	8	MQFVEFPLT	BBAABBbBB
X	kappa	Homo.sapiens	Hu_IGKV2-40*01	97.1	Hu_IGKV2-40*01	83.3	L4	6	L4-6-3	9	GSDTDF	EBAABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022