PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6MQS

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	89.0	CDRLenMismatch	-1.0	H1	14	H1-14-2	11	GVSGGSISDaYYWS	BBBLBBAABBBBBB
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	89.0	Ma_IGHV4-2*01	50.0	H2	10	H2-10-1	10	YIFGSNGGTR	BBBAAALBBB
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	89.0	Ma_IGHV4-2*01	50.0	H3	14	H3-14-*	-1	VREGVPTEATTGDH	BBAEBBBABBAEBB
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	89.0	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	7	IDTSKNQL	BBAAALBB
B	lambda	Macaca.mulatta	Ma_IGLV1-7*01	92.6	Ma_IGLV1-7*01	69.2	L1	13	L1-13-1	11	TGTNSNIGVNYVQ	BBBAAAAAABBBB
B	lambda	Macaca.mulatta	Ma_IGLV1-7*01	92.6	Ma_IGLV1-7*01	87.5	L2	8	L2-8-1	7	YENYKRPS	BLLABBBB
B	lambda	Macaca.mulatta	Ma_IGLV1-7*01	92.6	Ma_IGLV1-7*01	77.8	L3	11	L3-11-1	11	QSYDISLGAHV	BBBBAAALBBB
B	lambda	Macaca.mulatta	Ma_IGLV1-7*01	92.6	Ma_IGLV1-7*01	83.3	L4	6	L4-6-2	13	QSGSSA	BBEABB
C	heavy	Macaca.mulatta	Ma_IGHV4-2*01	89.0	CDRLenMismatch	-1.0	H1	14	H1-14-2	12	GVSGGSISDaYYWS	BBBLBBAABBBBBB
C	heavy	Macaca.mulatta	Ma_IGHV4-2*01	89.0	Ma_IGHV4-2*01	50.0	H2	10	H2-10-1	11	YIFGSNGGTR	BBBAAALBBB
C	heavy	Macaca.mulatta	Ma_IGHV4-2*01	89.0	Ma_IGHV4-2*01	50.0	H3	14	H3-14-*	-1	VREGVPTEATTGDH	BBAEBBBABBAEBB
C	heavy	Macaca.mulatta	Ma_IGHV4-2*01	89.0	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	9	IDTSKNQL	BBAAALBB
D	lambda	Macaca.mulatta	Ma_IGLV1-7*01	92.6	Ma_IGLV1-7*01	69.2	L1	13	L1-13-1	11	TGTNSNIGVNYVQ	BBBAAAAAABBBB
D	lambda	Macaca.mulatta	Ma_IGLV1-7*01	92.6	Ma_IGLV1-7*01	87.5	L2	8	L2-8-1	7	YENYKRPS	BLLABBBB
D	lambda	Macaca.mulatta	Ma_IGLV1-7*01	92.6	Ma_IGLV1-7*01	77.8	L3	11	L3-11-1	10	QSYDISLGAHV	BBBBAAALBBB
D	lambda	Macaca.mulatta	Ma_IGLV1-7*01	92.6	Ma_IGLV1-7*01	83.3	L4	6	L4-6-2	14	QSGSSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022