PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6MQR

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	79.5	CDRLenMismatch	-1.0	H1	15	H1-15-1	21	AVSGDTISSpyYFWS	BBBLBBAABBLBBBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	79.5	Ma_IGHV4-2*01	0.0	H2	10	H2-10-*	-1	GLYSNTMDVY	EBBAABABBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	79.5	Ma_IGHV4-2*01	100.0	H3	15	H3-15-*	-1	ARERVVAhNYYGLDL
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	79.5	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	10	RDTSKNHF	BBAAALBB
L	kappa	Macaca.mulatta	Ma_IGKV1-13*01	89.9	Ma_IGKV1-13*01	63.6	L1	11	L1-11-1	5	RASQDIKNSLS	BBABBAEABBB
L	kappa	Macaca.mulatta	Ma_IGKV1-13*01	89.9	Ma_IGKV1-13*01	37.5	L2	8	L2-8-1	11	HHSSTLET	BLLABBBB
L	kappa	Macaca.mulatta	Ma_IGKV1-13*01	89.9	Ma_IGKV1-13*01	28.6	L3	9	L3-9-cis7-1	6	QQYEDFPLT	BBAABBbBB
L	kappa	Macaca.mulatta	Ma_IGKV1-13*01	89.9	Ma_IGKV1-13*01	83.3	L4	6	L4-6-1	13	GYGTEF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022