PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6MQE

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	82.2	CDRLenMismatch	-1.0	H1	15	H1-15-*	-1	EVSSGSTSRdfFYWS	BBBBBABAABBBBBB
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	82.2	Ma_IGHV4-2*01	10.0	H2	10	H2-10-*	-1	GMYSNSEETN	BBBAABABBB
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	82.2	Ma_IGHV4-2*01	0.0	H3	19	H3-19-*	-1	SSRAKIYYSAsysggRIDV
A	heavy	Macaca.mulatta	Ma_IGHV4-2*01	82.2	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	8	KDTSKNEF	BBAAALBB
B	kappa	Macaca.mulatta	Ma_IGKV1-10*01	84.1	Ma_IGKV1-10*01	72.7	L1	11	L1-11-*	-1	RASQGIDKDLS	BBABBAAABBB
B	kappa	Macaca.mulatta	Ma_IGKV1-10*01	84.1	Ma_IGKV1-10*01	50.0	L2	8	L2-8-1	8	YTASTLQT	BLLABBBB
B	kappa	Macaca.mulatta	Ma_IGKV1-10*01	84.1	Ma_IGKV1-10*01	14.3	L3	9	L3-9-cis7-1	8	QQDFSFPLT	BBAABBbBB
B	kappa	Macaca.mulatta	Ma_IGKV1-10*01	84.1	Ma_IGKV1-10*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	82.2	CDRLenMismatch	-1.0	H1	15	H1-15-*	-1	EVSSGSTSRdfFYWS	BBBBBABAABBBBBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	82.2	Ma_IGHV4-2*01	10.0	H2	10	H2-10-*	-1	GMYSNSEETN	BBBAABABBB
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	82.2	Ma_IGHV4-2*01	0.0	H3	19	H3-19-*	-1	SSRAKIYYSAsysggRIDV
H	heavy	Macaca.mulatta	Ma_IGHV4-2*01	82.2	Ma_IGHV4-2*01	75.0	H4	8	H4-8-1	10	KDTSKNEF	BBAAALBB
L	kappa	Macaca.mulatta	Ma_IGKV1-10*01	84.1	Ma_IGKV1-10*01	72.7	L1	11	L1-11-*	-1	RASQGIDKDLS	BBABBAAABBB
L	kappa	Macaca.mulatta	Ma_IGKV1-10*01	84.1	Ma_IGKV1-10*01	50.0	L2	8	L2-8-1	8	YTASTLQT	BLLABBBB
L	kappa	Macaca.mulatta	Ma_IGKV1-10*01	84.1	Ma_IGKV1-10*01	14.3	L3	9	L3-9-cis7-1	8	QQDFSFPLT	BBAABBbBB
L	kappa	Macaca.mulatta	Ma_IGKV1-10*01	84.1	Ma_IGKV1-10*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022