PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6MNR

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Macaca.mulatta	Ma_IGHV3-18*01	91.8	Ma_IGHV3-18*01	69.2	H1	13	H1-13-1	16	EVSGLTFSNSWMS	BBBLBBAAABBBB
H	heavy	Macaca.mulatta	Ma_IGHV3-18*01	91.8	Ma_IGHV3-18*01	91.7	H2	12	H2-12-*	-1	FIKTKadGGTAA	BBBBAABALBBB
H	heavy	Macaca.mulatta	Ma_IGHV3-18*01	91.8	Ma_IGHV3-18*01	0.0	H3	13	H3-13-*	-1	QGAVVISHEYIEI	BBBBBBLLBBBBB
H	heavy	Macaca.mulatta	Ma_IGHV3-18*01	91.8	Ma_IGHV3-18*01	87.5	H4	8	H4-8-1	6	RDDSKNTV	BBAAALBB
L	lambda	Macaca.mulatta	Ma_IGLV1-15*01	95.6	Ma_IGLV1-15*01	76.9	L1	13	L1-13-1	8	SGGSSNIGDDSVS	BBBAAAAAABBBB
L	lambda	Macaca.mulatta	Ma_IGLV1-15*01	95.6	Ma_IGLV1-15*01	87.5	L2	8	L2-8-1	7	YYNDRRAS	BLLABBBB
L	lambda	Macaca.mulatta	Ma_IGLV1-15*01	95.6	Ma_IGLV1-15*01	88.9	L3	11	L3-11-1	10	AAWDDSLSAYI	BBBBAAALBBB
L	lambda	Macaca.mulatta	Ma_IGLV1-15*01	95.6	Ma_IGLV1-15*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022