PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6GWN

#CDRs = 4; #Clusters = 6.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
B	heavy	Vicugna.pacos	Al_IGHV3S57*01_VHH	86.3	Al_IGHV3S57*01_VHH	69.2	H1	13	H1-13-1	11	AASGFTFRTYAMQ	BBBLBBAAABBBB
B	heavy	Vicugna.pacos	Al_IGHV3S57*01_VHH	86.3	CDRLenMismatch	-1.0	H2	10	H2-10-6	18	AISNIGGVTD	BBBABLLBBB
B	heavy	Vicugna.pacos	Al_IGHV3S57*01_VHH	86.3	Al_IGHV3S57*01_VHH	0.0	H3	9	H3-9-*	-1	SAVRLPQRY	BBBBBaBBB
B	heavy	Vicugna.pacos	Al_IGHV3S57*01_VHH	86.3	Al_IGHV3S57*01_VHH	75.0	H4	8	H4-8-1	10	RDNAKTTV	BBAAALBB
C	heavy	Vicugna.pacos	Al_IGHV3S66*01_VHH	97.3	Al_IGHV3S66*01_VHH	84.6	H1	13	H1-13-1	14	AASGFTFDDYSIA	BBBLBBAAABBBB
C	heavy	Vicugna.pacos	Al_IGHV3S66*01_VHH	97.3	Al_IGHV3S66*01_VHH	90.0	H2	10	H2-10-1	16	CISSSDGSAY	BBBAAALBBB
C	heavy	Vicugna.pacos	Al_IGHV3S66*01_VHH	97.3	Al_IGHV3S66*01_VHH	0.0	H3	14	H3-14-*	-1	AAVWARVCRNPYDY	BBBBBABBBBbBAB
C	heavy	Vicugna.pacos	Al_IGHV3S66*01_VHH	97.3	Al_IGHV3S66*01_VHH	100.0	H4	8	H4-8-1	8	SDNAKNTV	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022