PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6FLA

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Mus.musculus	Mo_IGHV1-87*01	87.7	Mo_IGHV1-87*01	92.3	H1	13	H1-13-1	9	KASGYTFTSYWLQ	BBBLBBAAABBBB
A	heavy	Mus.musculus	Mo_IGHV1-87*01	87.7	Mo_IGHV1-87*01	80.0	H2	10	H2-10-1	11	AIWPGDDDTR	BBBAAALBBB
A	heavy	Mus.musculus	Mo_IGHV1-87*01	87.7	Mo_IGHV1-87*01	50.0	H3	10	H3-10-*	-1	ARKGGFAMDY	BBBABABBAB
A	heavy	Mus.musculus	Mo_IGHV1-87*01	87.7	Mo_IGHV1-87*01	100.0	H4	8	H4-8-1	9	ADKSSSTA	BBAAALBB
B	kappa	Mus.musculus	Mo_IGKV3-10*01	92.8	Mo_IGKV3-10*01	86.7	L1	15	L1-15-1	8	RASESVdsfgKSFMH	BBABBABBLLBBBBB
B	kappa	Mus.musculus	Mo_IGKV3-10*01	92.8	Mo_IGKV3-10*01	87.5	L2	8	L2-8-1	9	HLASNLES	BLLABBBB
B	kappa	Mus.musculus	Mo_IGKV3-10*01	92.8	Mo_IGKV3-10*01	85.7	L3	9	L3-9-cis7-1	5	QQNNEVPFT	BBAABBbBB
B	kappa	Mus.musculus	Mo_IGKV3-10*01	92.8	Mo_IGKV3-10*01	100.0	L4	6	L4-6-1	6	GSRTDF	EBEABB
H	heavy	Mus.musculus	Mo_IGHV1-87*01	87.7	Mo_IGHV1-87*01	92.3	H1	13	H1-13-1	9	KASGYTFTSYWLQ	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV1-87*01	87.7	Mo_IGHV1-87*01	80.0	H2	10	H2-10-1	11	AIWPGDDDTR	BBBAAALBBB
H	heavy	Mus.musculus	Mo_IGHV1-87*01	87.7	Mo_IGHV1-87*01	50.0	H3	10	H3-10-*	-1	ARKGGFAMDY	BBBABABBAB
H	heavy	Mus.musculus	Mo_IGHV1-87*01	87.7	Mo_IGHV1-87*01	100.0	H4	8	H4-8-1	10	ADKSSSTA	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV3-10*01	92.8	Mo_IGKV3-10*01	86.7	L1	15	L1-15-1	8	RASESVdsfgKSFMH	BBABBABBLLBBBBB
L	kappa	Mus.musculus	Mo_IGKV3-10*01	92.8	Mo_IGKV3-10*01	87.5	L2	8	L2-8-1	9	HLASNLES	BLLABBBB
L	kappa	Mus.musculus	Mo_IGKV3-10*01	92.8	Mo_IGKV3-10*01	85.7	L3	9	L3-9-cis7-1	5	QQNNEVPFT	BBAABBbBB
L	kappa	Mus.musculus	Mo_IGKV3-10*01	92.8	Mo_IGKV3-10*01	100.0	L4	6	L4-6-1	7	GSRTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022