PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6EDU

#CDRs = 8; #Clusters = 14.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
J	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	76.9	H1	13	H1-13-*	-1	KVSGFTLTGLSIH	BBBLBBBALAABB
J	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	60.0	H2	10	H2-10-*	-1	GFGPEENEII	EBBABAABBB
J	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	100.0	H3	18	H3-18-*	-1	ATGGNYYNlwtgYYPLAY
J	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	87.5	H4	8	H4-8-1	17	EDTSTNTA	BBAAALBB
K	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	92.3	L1	13	L1-13-*	-1	SGSSSNIGKNYVS	BBBAAAAAABBBB
K	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	50.0	L2	8	L2-8-*	-1	FDDTQRPS	BLLABBBA
K	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	88.9	L3	12	L3-12-*	-1	GTWDSSLSTgQL
K	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	19	KSGTSA	BBEABB
L	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	76.9	H1	13	H1-13-*	-1	KVSGFTLTGLSIH	BBBLBBBALAABB
L	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	60.0	H2	10	H2-10-*	-1	GFGPEENEII	EBBABAABBB
L	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	100.0	H3	18	H3-18-*	-1	ATGGNYYNlwtgYYPLAY
L	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	87.5	H4	8	H4-8-1	17	EDTSTNTA	BBAAALBB
M	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	92.3	L1	13	L1-13-*	-1	SGSSSNIGKNYVS	BBBAAAAAABBBB
M	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	50.0	L2	8	L2-8-*	-1	FDDTQRPS	BLLABBBA
M	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	88.9	L3	12	L3-12-*	-1	GTWDSSLSTgQL
M	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	19	KSGTSA	BBEABB
N	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	76.9	H1	13	H1-13-*	-1	KVSGFTLTGLSIH	BBBLBBBALAABB
N	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	60.0	H2	10	H2-10-*	-1	GFGPEENEII	EBBABAABBB
N	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	100.0	H3	18	H3-18-*	-1	ATGGNYYNlwtgYYPLAY
N	heavy	Homo.sapiens	Hu_IGHV1-24*01	94.5	Hu_IGHV1-24*01	87.5	H4	8	H4-8-1	17	EDTSTNTA	BBAAALBB
O	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	92.3	L1	13	L1-13-*	-1	SGSSSNIGKNYVS	BBBAAAAAABBBB
O	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	50.0	L2	8	L2-8-*	-1	FDDTQRPS	BLLABBBA
O	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	88.9	L3	12	L3-12-*	-1	GTWDSSLSTgQL
O	lambda	Homo.sapiens	Hu_IGLV1-51*01	97.1	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	19	KSGTSA	BBEABB
P	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H1	14	H1-14-*	-1	KAYGVnTFGLYAVN	BBBLBABAAABBBB
P	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H2	9	H2-9-*	-1	QIWRWKSSA
P	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H3	22	H3-22-*	-1	TTTSTYDKWSglhhdgvmAFSS
P	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H4	12	H4-12-*	-1	AVDltgsSPPIS
Q	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	0.0	L1	12	L1-12-2	22	RASQSITgNWVA	BBABBBBLLBBB
Q	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	25.0	L2	8	L2-8-*	-1	YRGAALLG	BLLABBBA
Q	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	42.9	L3	9	L3-9-cis7-1	22	QQYDTYPGT	BBBABBbBB
Q	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	66.7	L4	6	L4-6-2	27	AAGTDF	BAEABB
R	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H1	14	H1-14-*	-1	KAYGVnTFGLYAVN	BBBLBABAAABBBB
R	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H2	9	H2-9-*	-1	QIWRWKSSA
R	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H3	22	H3-22-*	-1	TTTSTYDKWSglhhdgvmAFSS
R	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H4	12	H4-12-*	-1	AVDltgsSPPIS
S	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	0.0	L1	12	L1-12-2	22	RASQSITgNWVA	BBABBBBLLBBB
S	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	25.0	L2	8	L2-8-*	-1	YRGAALLG	BLEABBBA
S	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	42.9	L3	9	L3-9-cis7-1	22	QQYDTYPGT	BBBABBbBB
S	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	66.7	L4	6	L4-6-2	27	AAGTDF	BAEABB
T	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H1	14	H1-14-*	-1	KAYGVnTFGLYAVN	BBBLBABAAABBBB
T	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H2	9	H2-9-*	-1	QIWRWKSSA
T	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H3	22	H3-22-*	-1	TTTSTYDKWSglhhdgvmAFSS
T	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H4	12	H4-12-*	-1	AVDltgsSPPIS
U	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	0.0	L1	12	L1-12-2	22	RASQSITgNWVA	BBABBBBLLBBB
U	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	25.0	L2	8	L2-8-*	-1	YRGAALLG	BLEABBBA
U	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	42.9	L3	9	L3-9-cis7-1	22	QQYDTYPGT	BBBABBbBB
U	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	66.7	L4	6	L4-6-2	27	AAGTDF	BAEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022