PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6CHB

#CDRs = 8; #Clusters = 18.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	76.9	H1	13	H1-13-*	-1	TASGYKFTGYHMH	BBBLBBABLBBBB
D	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	50.0	H2	10	H2-10-6	17	WINPFRGAVK	BBBABLLBBB
D	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	100.0	H3	19	H3-19-*	-1	AREMFDSSADWspwrgMVA
D	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	50.0	H4	8	H4-8-*	-1	RDTSMEIF	BBALALBB
E	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	57.1	L1	14	L1-14-*	-1	AGSSRDVGGfDLVS	BBBAAAAAABAABB
E	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	75.0	L2	8	L2-8-1	18	YEVNKRPS	BLEBBBBB
E	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	0.0	L3	8	L3-8-*	-1	YSYADGVA	BBBBEBBB
E	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	100.0	L4	6	L4-6-2	19	KSGNTA	BBEABB
I	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	None	-1.0	H1	14	H1-14-*	-1	TVSQDSrPSDHSWT	BBBLBABAAABBBB
I	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	None	-1.0	H2	9	H2-9-1	21	DIHYNGATT	BBBAALBBB
I	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	Hu_IGHV4-OR15-8*02	100.0	H3	23	H3-23-*	-1	ARNAIRIYgvvalgewfHYGMDV
I	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	Hu_IGHV4-OR15-8*02	37.5	H4	8	H4-8-*	-1	LDQSIPRF	BBAAAbBB
J	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	None	-1.0	H1	14	H1-14-*	-1	TVSQDSrPSDHSWT	BBBLBABAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	None	-1.0	H2	9	H2-9-1	21	DIHYNGATT	BBBAALBBB
J	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	Hu_IGHV4-OR15-8*02	100.0	H3	23	H3-23-*	-1	ARNAIRIYgvvalgewfHYGMDV
J	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	Hu_IGHV4-OR15-8*02	37.5	H4	8	H4-8-*	-1	LDQSIPRF	BBAAAbBB
K	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	None	36.4	L1	11	L1-11-4	18	SGAPLTSRFTY	BEAAAAABBBB
K	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	None	37.5	L2	8	L2-8-*	-1	SRSSQrss
K	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	Hu_IGLV3-25*02	55.6	L3	11	L3-11-2	17	QSSDTSDSYKM	BBBBAALABBB
K	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	Hu_IGLV3-25*02	83.3	L4	6	L4-6-2	31	WSGTTV	BBEABB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	None	36.4	L1	11	L1-11-*	-1	SGAPLTSRFTY	BEAAAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	None	37.5	L2	8	L2-8-*	-1	SRSSQrss
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	Hu_IGLV3-25*02	55.6	L3	11	L3-11-2	24	QSSDTSDSYKM	BBBBAALABBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	Hu_IGLV3-25*02	83.3	L4	6	L4-6-2	27	WSGTTV	BBEABB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	76.9	H1	13	H1-13-1	18	TASGYKFTGYHMH	BBBLBBAAABBBB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	50.0	H2	10	H2-10-6	14	WINPFRGAVK	BBBABLLBBB
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	100.0	H3	19	H3-19-*	-1	AREMFDSSADWspwrgMVA
M	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	50.0	H4	8	H4-8-1	27	RDTSMEIF	BBAAALBB
N	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	57.1	L1	14	L1-14-2	20	AGSSRDVGGfDLVS	BBBAAAAAABABBB
N	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	75.0	L2	8	L2-8-*	-1	YEVNKRPS	BLEBBBBB
N	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	0.0	L3	8	L3-8-*	-1	YSYADGVA	BBBBEABB
N	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	100.0	L4	6	L4-6-2	20	KSGNTA	BBEABB
O	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	76.9	H1	13	H1-13-*	-1	TASGYKFTGYHMH	BBBLBBAAABBBB
O	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	50.0	H2	10	H2-10-6	19	WINPFRGAVK	BBBABLLBBB
O	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	100.0	H3	19	H3-19-*	-1	AREMFDSSADWspwrgMVA
O	heavy	Homo.sapiens	Hu_IGHV1-2*02	80.8	Hu_IGHV1-2*02	50.0	H4	8	H4-8-1	22	RDTSMEIF	BBAAALBB
P	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	57.1	L1	14	L1-14-2	20	AGSSRDVGGfDLVS	BBBAABAAABBABB
P	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	75.0	L2	8	L2-8-*	-1	YEVNKRPS	BLEBBBBB
P	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	0.0	L3	8	L3-8-*	-1	YSYADGVA	BBBBEBBB
P	lambda	Homo.sapiens	Hu_IGLV2-14*02	91.2	Hu_IGLV2-14*02	100.0	L4	6	L4-6-2	30	KSGNTA	BBEABB
Q	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	None	-1.0	H1	14	H1-14-*	-1	TVSQDSrPSDHSWT	BBBLBABAAABBBB
Q	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	None	-1.0	H2	9	H2-9-1	11	DIHYNGATT	BBBAALBBB
Q	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	Hu_IGHV4-OR15-8*02	100.0	H3	23	H3-23-*	-1	ARNAIRIYgvvalgewfHYGMDV
Q	heavy	Homo.sapiens	Hu_IGHV4-OR15-8*02	76.7	Hu_IGHV4-OR15-8*02	37.5	H4	8	H4-8-*	-1	LDQSIPRF	BBAAAbBB
R	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	None	36.4	L1	11	L1-11-4	19	SGAPLTSRFTY	BBAAAAABBBB
R	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	None	37.5	L2	8	L2-8-*	-1	SRSSQrss
R	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	Hu_IGLV3-25*02	55.6	L3	11	L3-11-2	11	QSSDTSDSYKM	BBBBAALABBB
R	lambda	Homo.sapiens	Hu_IGLV3-25*02	86.4	Hu_IGLV3-25*02	83.3	L4	6	L4-6-2	21	WSGTTV	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022