PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6CBV

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV5-12*01	46.2	H1	13	H1-13-1	9	AASGFNVVDFSLH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV5-12*01	60.0	H2	10	H2-10-1	11	YISSSSGSTS	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	17	H3-17-*	-1	ARWGYWPgepWWKAFDY
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	4	ADTSKNTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	72.7	L1	11	L1-11-1	6	RASQSVSSAVA	BBABBAEABBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	62.5	L2	8	L2-8-1	6	YSASSLYS	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	28.6	L3	10	L3-10-*	-1	QQYLYYsLVT	BBAABAAABB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	11	RSGTDF	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022