PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6CA6

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	58.3	L1	12	L1-12-1	9	RATQSVGgDYFA	BBABBBBAAABB
A	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	62.5	L2	8	L2-8-1	5	YGTSRRAA	BLEABBBB
A	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	42.9	L3	8	L3-8-*	-1	RQYETSFT	BBAAABAB
A	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	61.5	H1	13	H1-13-1	15	VGSEFTFSEAWMT	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	33.3	H2	12	H2-12-1	16	HMRPttEGGAKD	BBBBAAALLBBB
B	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	50.0	H3	25	H3-25-*	-1	MTGvergdfwsddySQHYNTYLIDV
B	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	87.5	H4	8	H4-8-1	7	RDDSKSTL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	61.5	H1	13	H1-13-1	16	VGSEFTFSEAWMT	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	33.3	H2	12	H2-12-1	16	HMRPttEGGAKD	BBBBAAALLBBB
H	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	50.0	H3	25	H3-25-*	-1	MTGvergdfwsddySQHYNTYLIDV
H	heavy	Homo.sapiens	Hu_IGHV3-15*07	90.4	Hu_IGHV3-15*07	87.5	H4	8	H4-8-1	7	RDDSKSTL	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	58.3	L1	12	L1-12-1	10	RATQSVGgDYFA	BBABBBBAAABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	62.5	L2	8	L2-8-1	5	YGTSRRAA	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	42.9	L3	8	L3-8-*	-1	RQYETSFT	BBAAABAB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022