PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 6AZX

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-23*05	91.8	Ra_IGHV5-54*01	76.9	H1	13	H1-13-1	13	VVSGFTFSNYAFN	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-23*05	91.8	Ra_IGHV5-54*01	40.0	H2	10	H2-10-*	-1	IIYRSGSRMY	BBBAALBBBB
A	heavy	Homo.sapiens	Hu_IGHV3-23*05	91.8	Hu_IGHV3-23*05	0.0	H3	14	H3-14-*	-1	TTLLIYESDVGVDF	BAEBBBBLLBBBBB
A	heavy	Homo.sapiens	Hu_IGHV3-23*05	91.8	Hu_IGHV3-23*05	87.5	H4	8	H4-8-1	5	RDDSKNTL	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Ra_IGKV3S13*01	26.7	L1	15	L1-15-*	-1	RSTQSLifgeHNYLD	BBABBABBEABBBBB
B	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Ra_IGKV3S13*01	75.0	L2	8	L2-8-1	7	YLASNRAS	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Hu_IGKV2-28*01	42.9	L3	9	L3-9-cis7-1	8	VQTVQVPYT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Hu_IGKV2-28*01	83.3	L4	6	L4-6-1	5	GSGTYF	EBEABB
C	heavy	Homo.sapiens	Hu_IGHV3-23*05	91.8	Ra_IGHV5-54*01	76.9	H1	13	H1-13-1	13	VVSGFTFSNYAFN	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV3-23*05	91.8	Ra_IGHV5-54*01	40.0	H2	10	H2-10-2	15	IIYRSGSRMY	BBBAALABBB
C	heavy	Homo.sapiens	Hu_IGHV3-23*05	91.8	Hu_IGHV3-23*05	0.0	H3	14	H3-14-*	-1	TTLLIYESDVGVDF	BAEBBBBLLBBBBB
C	heavy	Homo.sapiens	Hu_IGHV3-23*05	91.8	Hu_IGHV3-23*05	87.5	H4	8	H4-8-1	5	RDDSKNTL	BBAAALBB
D	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Ra_IGKV3S13*01	26.7	L1	15	L1-15-*	-1	RSTQSLifgeHNYLD	BBABBABBEABBBBB
D	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Ra_IGKV3S13*01	75.0	L2	8	L2-8-1	7	YLASNRAS	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Hu_IGKV2-28*01	42.9	L3	9	L3-9-cis7-1	8	VQTVQVPYT	BBAABBbBB
D	kappa	Homo.sapiens	Hu_IGKV2-28*01	95.7	Hu_IGKV2-28*01	83.3	L4	6	L4-6-1	5	GSGTYF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022