PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5WTT

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Mus.musculus	Mo_IGHV3-1*02	94.4	Mo_IGHV3-1*02	92.9	H1	14	H1-14-*	-1	TVTGYSITsDYSWH	BBAABBAAAABBBB
A	heavy	Mus.musculus	Mo_IGHV3-1*02	94.4	Mo_IGHV3-1*02	100.0	H2	9	H2-9-1	10	YIHYSGSTN	BBBAALBBB
A	heavy	Mus.musculus	Mo_IGHV3-1*02	94.4	Mo_IGHV3-1*02	100.0	H3	12	H3-12-1	12	ARGTIYEGSLDY	BBBBAAALBBAB
A	heavy	Mus.musculus	Mo_IGHV3-1*02	94.4	Mo_IGHV3-1*02	100.0	H4	8	H4-8-1	9	RDTSKNQF	BBAAALBB
B	kappa	Homo.sapiens	Mo_IGKV1-133*01	95.7	Mo_IGKV1-133*01	93.8	L1	16	L1-16-1	6	KSSQSLlysdgKTYLN	BBABBABBAALBBBBB
B	kappa	Homo.sapiens	Mo_IGKV1-133*01	95.7	Mo_IGKV1-133*01	100.0	L2	8	L2-8-*	-1	YLVSKLDS	BLEABBBA
B	kappa	Homo.sapiens	Mo_IGKV1-133*01	95.7	Mo_IGKV1-133*01	100.0	L3	9	L3-9-cis7-1	17	VQGTHFPQT	BBAABBbBB
B	kappa	Homo.sapiens	Mo_IGKV1-133*01	95.7	Mo_IGKV1-133*01	83.3	L4	6	L4-6-1	4	GSGIDF	EBEABB
H	heavy	Mus.musculus	Mo_IGHV3-1*02	94.4	Mo_IGHV3-1*02	92.9	H1	14	H1-14-*	-1	TVTGYSITsDYSWH	BBBLBBAAAABBBB
H	heavy	Mus.musculus	Mo_IGHV3-1*02	94.4	Mo_IGHV3-1*02	100.0	H2	9	H2-9-1	10	YIHYSGSTN	BBBAALBBB
H	heavy	Mus.musculus	Mo_IGHV3-1*02	94.4	Mo_IGHV3-1*02	100.0	H3	12	H3-12-1	9	ARGTIYEGSLDY	BBBBAAALBBAB
H	heavy	Mus.musculus	Mo_IGHV3-1*02	94.4	Mo_IGHV3-1*02	100.0	H4	8	H4-8-1	9	RDTSKNQF	BBAAALBB
L	kappa	Homo.sapiens	Mo_IGKV1-133*01	95.7	Mo_IGKV1-133*01	93.8	L1	16	L1-16-1	7	KSSQSLlysdgKTYLN	BBABBABBAALBBBBB
L	kappa	Homo.sapiens	Mo_IGKV1-133*01	95.7	Mo_IGKV1-133*01	100.0	L2	8	L2-8-*	-1	YLVSKLDS	BLEABBBA
L	kappa	Homo.sapiens	Mo_IGKV1-133*01	95.7	Mo_IGKV1-133*01	100.0	L3	9	L3-9-cis7-1	14	VQGTHFPQT	BBAABBbBB
L	kappa	Homo.sapiens	Mo_IGKV1-133*01	95.7	Mo_IGKV1-133*01	83.3	L4	6	L4-6-1	17	GSGIDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022