PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5W1K

#CDRs = 8; #Clusters = 15.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	81.8	L1	11	L1-11-*	-1	RASQSIDNWLA	BBABBBABABB
A	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	75.0	L2	8	L2-8-1	17	YTASRLES	BLLABBBB
A	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	0.0	L3	4	L3-4-*	-1	QHRT
A	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	100.0	L4	6	L4-6-1	17	GSGTEF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	92.3	H1	13	H1-13-1	18	AASGFTFSSSAMH	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	60.0	H2	10	H2-10-*	-1	VIWSDGSNEN	BBBBLELBBB
B	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	50.0	H3	19	H3-19-*	-1	ATDKTYvsgytSTWYYFNY
B	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	100.0	H4	8	H4-8-1	13	RDNSKNTL	BBAAALBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	100.0	L1	12	L1-12-*	-1	RASQSVSsSYLA	BBABBBBAEABB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	87.5	L2	8	L2-8-1	21	YGASGRAT	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	71.4	L3	9	L3-9-*	-1	QQYGRSGYT	BBBBLLEBB
C	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	18	GSGTDF	EBEABB
D	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	CDRLenMismatch	-1.0	H1	15	H1-15-*	-1	SVSGGSIggSSYYWS	BBABBBABALABBBB
D	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	55.6	H2	9	H2-9-1	25	YINYRGITH	BBBAALBBB
D	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	100.0	H3	18	H3-18-*	-1	ARLTSDcsggNCYQAFDY
D	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	62.5	H4	8	H4-8-1	17	VETSQNHF	BBAAALBB
F	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	81.8	L1	11	L1-11-*	-1	RASQSIDNWLA	BBABBBABBBB
F	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	75.0	L2	8	L2-8-*	-1	YTASRLES	BLEABBBB
F	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	0.0	L3	4	L3-4-*	-1	QHRT
F	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	100.0	L4	6	L4-6-1	17	GSGTEF	EBEABB
G	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	92.3	H1	13	H1-13-1	17	AASGFTFSSSAMH	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	60.0	H2	10	H2-10-*	-1	VIWSDGSNEN	BBBBLEEBAB
G	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	50.0	H3	19	H3-19-*	-1	ATDKTYvsgytSTWYYFNY
G	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	100.0	H4	8	H4-8-1	16	RDNSKNTL	BBAAALBB
H	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	100.0	L1	12	L1-12-*	-1	RASQSVSsSYLA	BBABBBBAABBB
H	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	87.5	L2	8	L2-8-1	21	YGASGRAT	BLLABBBB
H	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	71.4	L3	9	L3-9-*	-1	QQYGRSGYT	BEBBLEEBB
H	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	18	GSGTDF	EBEABB
I	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	CDRLenMismatch	-1.0	H1	15	H1-15-*	-1	SVSGGSIggSSYYWS	BBAAEBBBBELBBBB
I	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	55.6	H2	9	H2-9-1	23	YINYRGITH	BBBAALBBB
I	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	100.0	H3	18	H3-18-*	-1	ARLTSDcsggNCYQAFDY
I	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	62.5	H4	8	H4-8-1	14	VETSQNHF	BBAAALBB
K	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	81.8	L1	11	L1-11-*	-1	RASQSIDNWLA	BBABBBAABBB
K	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	75.0	L2	8	L2-8-1	16	YTASRLES	BLLABBBB
K	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	0.0	L3	4	L3-4-*	-1	QHRT
K	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	100.0	L4	6	L4-6-1	16	GSGTEF	EBEABB
L	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	92.3	H1	13	H1-13-1	15	AASGFTFSSSAMH	BBBLBBAAABBBB
L	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	60.0	H2	10	H2-10-*	-1	VIWSDGSNEN	BBBBLELBBB
L	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	50.0	H3	19	H3-19-*	-1	ATDKTYvsgytSTWYYFNY
L	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	100.0	H4	8	H4-8-1	14	RDNSKNTL	BBAAALBB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	100.0	L1	12	L1-12-*	-1	RASQSVSsSYLA	BBABBBAEAABB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	87.5	L2	8	L2-8-1	20	YGASGRAT	BLLABBBB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	71.4	L3	9	L3-9-1	26	QQYGRSGYT	BBBBLLEBB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	17	GSGTDF	EBEABB
N	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	100.0	L1	12	L1-12-*	-1	RASQSVSsSYLA	BBABBBAELABB
N	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	87.5	L2	8	L2-8-1	21	YGASGRAT	BLLABBBB
N	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	71.4	L3	9	L3-9-*	-1	QQYGRSGYT	BBBBLLEBB
N	kappa	Homo.sapiens	Hu_IGKV3-20*01	98.5	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	19	GSGTDF	EBEABB
O	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	CDRLenMismatch	-1.0	H1	15	H1-15-*	-1	SVSGGSIggSSYYWS	BBBLBBBEEBLBBBB
O	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	55.6	H2	9	H2-9-1	24	YINYRGITH	BBBAALBBB
O	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	100.0	H3	18	H3-18-*	-1	ARLTSDcsggNCYQAFDY
O	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	62.5	H4	8	H4-8-1	12	VETSQNHF	BBAAALBB
Q	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	CDRLenMismatch	-1.0	H1	15	H1-15-*	-1	SVSGGSIggSSYYWS	BBBLBAEBAAABBBB
Q	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	55.6	H2	9	H2-9-1	23	YINYRGITH	BBBAALBBB
Q	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	100.0	H3	18	H3-18-*	-1	ARLTSDcsggNCYQAFDY
Q	heavy	Homo.sapiens	Hu_IGHV4-59*04	84.7	Hu_IGHV4-59*04	62.5	H4	8	H4-8-1	14	VETSQNHF	BBAAALBB
S	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	81.8	L1	11	L1-11-*	-1	RASQSIDNWLA	BBABBBABABB
S	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	75.0	L2	8	L2-8-1	24	YTASRLES	BLLABBBB
S	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	0.0	L3	4	L3-4-*	-1	QHRT
S	kappa	Homo.sapiens	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	100.0	L4	6	L4-6-1	24	GSGTEF	EBEABB
T	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	92.3	H1	13	H1-13-1	16	AASGFTFSSSAMH	BBBLBBAAABBBB
T	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	60.0	H2	10	H2-10-*	-1	VIWSDGSNEN	BBBBLEEBAB
T	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	50.0	H3	19	H3-19-*	-1	ATDKTYvsgytSTWYYFNY
T	heavy	Homo.sapiens	Hu_IGHV3-30*15	100.0	Hu_IGHV3-30*15	100.0	H4	8	H4-8-1	13	RDNSKNTL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022