PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5TPL

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV1-2*07	80.8	Hu_IGHV1-2*07	69.2	H1	13	H1-13-1	9	KASGYTLSDYYVH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-2*07	80.8	Hu_IGHV1-2*07	70.0	H2	10	H2-10-1	15	WINPTSGRTI	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-2*07	80.8	Hu_IGHV1-2*07	100.0	H3	20	H3-20-*	-1	ARGGwislyvDYSYYPNFDS
H	heavy	Homo.sapiens	Hu_IGHV1-2*07	80.8	Hu_IGHV1-2*07	50.0	H4	8	H4-8-1	11	TDTSMNVA	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*02	89.7	Hu_IGLV2-14*02	92.9	L1	14	L1-14-2	10	TGSSSDVGSyNLVS	BBBAAAAAABABBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*02	89.7	Hu_IGLV2-14*02	50.0	L2	8	L2-8-1	10	YEVNKWAS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*02	89.7	Hu_IGLV2-14*02	55.6	L3	10	L3-10-1	15	SSSTNSATVI	BBBBAALBBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*02	89.7	Hu_IGLV2-14*02	100.0	L4	6	L4-6-2	15	KSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022