PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5TLK

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	93.3	L1	15	L1-15-1	7	KASQSVDyagdSYMN	BBABBABBLLBBBBB
A	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L2	8	L2-8-1	9	YAASNLES	BLLABBBB
A	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L3	9	L3-9-cis7-1	7	QQSNEDPYT	BBAABBbBB
A	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H1	13	H1-13-1	11	KASGYAFSSSWMN	BBBLBBAAABBBB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H2	10	H2-10-1	10	RIYPGDGDTN	BBBAAALBBB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H3	13	H3-13-*	-1	ARSDYYGDYGFAY	BBBABALAAEBAB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H4	8	H4-8-1	9	ADKSSSTA	BBAAALBB
C	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-33*01	100.0	Mo_IGKV3-12*01	66.7	L1	15	L1-15-*	-1	RASKSVSegrwSFMH	BBABBABBEABBBBB
C	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-33*01	100.0	Mo_IGKV3-12*01	75.0	L2	8	L2-8-1	7	YVASRLES	BLLABBBB
C	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-33*01	100.0	Hu_IGKV1-33*01	42.9	L3	9	L3-9-cis7-1	9	QHSRELPWT	BBAABBbBB
C	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-33*01	100.0	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB
D	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-11*05	98.6	Mo_IGHV5-12-2*01	92.3	H1	13	H1-13-1	6	AASGFTFSSYGMS	BBBLBBAAABBBB
D	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-11*05	98.6	Mo_IGHV5-12-2*01	60.0	H2	10	H2-10-2	11	YIDEGGGQTI	BBBAALABBB
D	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-11*05	98.6	Hu_IGHV3-11*05	100.0	H3	10	H3-10-*	-1	ARHRGNPFDY	BBBBEABBAB
D	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-11*05	98.6	Hu_IGHV3-11*05	100.0	H4	8	H4-8-1	9	RDNAKNSL	BBAAALBB
E	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	93.3	L1	15	L1-15-1	7	KASQSVDyagdSYMN	BBABBABBLLBBBBB
E	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L2	8	L2-8-1	10	YAASNLES	BLLABBBB
E	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L3	9	L3-9-cis7-1	6	QQSNEDPYT	BBAABBbBB
E	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H1	13	H1-13-1	11	KASGYAFSSSWMN	BBBLBBAAABBBB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H2	10	H2-10-1	10	RIYPGDGDTN	BBBAAALBBB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H3	13	H3-13-*	-1	ARSDYYGDYGFAY	BBBABALAAEBAB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H4	8	H4-8-1	14	ADKSSSTA	BBAAALBB
G	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-33*01	100.0	Mo_IGKV3-12*01	66.7	L1	15	L1-15-*	-1	RASKSVSegrwSFMH	BBABBABBEABBBBB
G	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-33*01	100.0	Mo_IGKV3-12*01	75.0	L2	8	L2-8-1	11	YVASRLES	BLLABBBB
G	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-33*01	100.0	Hu_IGKV1-33*01	42.9	L3	9	L3-9-cis7-1	9	QHSRELPWT	BBAABBbBB
G	kappa	Mus.musculus.Homo.sapiens	Hu_IGKV1-33*01	100.0	Hu_IGKV1-33*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
H	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-11*05	98.6	Mo_IGHV5-12-2*01	92.3	H1	13	H1-13-1	9	AASGFTFSSYGMS	BBBLBBAAABBBB
H	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-11*05	98.6	Mo_IGHV5-12-2*01	60.0	H2	10	H2-10-2	15	YIDEGGGQTI	BBBAALABBB
H	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-11*05	98.6	Hu_IGHV3-11*05	100.0	H3	10	H3-10-2	19	ARHRGNPFDY	BBBBEABBAB
H	heavy	Mus.musculus.Homo.sapiens	Hu_IGHV3-11*05	98.6	Hu_IGHV3-11*05	100.0	H4	8	H4-8-1	11	RDNAKNSL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022