PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5TLJ

#CDRs = 8; #Clusters = 14.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	93.3	L1	15	L1-15-1	18	KASQSVDyagdSYMN	BBABBABBLLBBBBB
A	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L2	8	L2-8-1	16	YAASNLES	BLLABBBB
A	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L3	9	L3-9-cis7-1	18	QQSNEDPYT	BBAABBbBB
A	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L4	6	L4-6-1	16	GSGTDF	EBEABB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H1	13	H1-13-*	-1	KASGYAFSSSWMN	BBBLAEAAABBBB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H2	10	H2-10-*	-1	RIYPGDGDTN	BBBBLALBBB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H3	13	H3-13-*	-1	ARSDYYGDYGFAY	BBBAAALAAEBAB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H4	8	H4-8-1	13	ADKSSSTA	BBAAALBB
C	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-12*01	100.0	Mo_IGKV3-12*01	93.3	L1	15	L1-15-*	-1	RASKSVSTsgysFMH	BBABBABBEABBBBB
C	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-12*01	100.0	Mo_IGKV3-12*01	100.0	L2	8	L2-8-1	15	YLASNLES	BLLABBBB
C	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-12*01	100.0	Mo_IGKV3-12*01	100.0	L3	9	L3-9-cis7-1	14	QHSRELPWT	BBAABBbBB
C	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-12*01	100.0	Mo_IGKV3-12*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
D	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV5-9*04	98.6	Mo_IGHV5-9*04	100.0	H1	13	H1-13-1	15	AASGFTFSSYTMS	BBBLBBAAABBBB
D	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV5-9*04	98.6	Mo_IGHV5-9*04	80.0	H2	10	H2-10-2	10	YISSGGGNTY	BBBAALABBB
D	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV5-9*04	98.6	Mo_IGHV5-9*04	50.0	H3	10	H3-10-2	22	SRHRGNPFDY	BBBBEABBAB
D	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV5-9*04	98.6	Mo_IGHV5-9*04	87.5	H4	8	H4-8-1	20	RDNARNTL	BBAAALBB
E	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	93.3	L1	15	L1-15-*	-1	KASQSVDyagdSYMN	BBABBABBBLBBBBB
E	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L2	8	L2-8-1	13	YAASNLES	BLEABBBB
E	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L3	9	L3-9-cis7-1	20	QQSNEDPYT	BBAABBbBB
E	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-4*01	100.0	Mo_IGKV3-4*01	100.0	L4	6	L4-6-1	22	GSGTDF	EBEABB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H1	13	H1-13-1	22	KASGYAFSSSWMN	BBBLBBAAABBBB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H2	10	H2-10-1	25	RIYPGDGDTN	BBBBAALBBB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H3	13	H3-13-*	-1	ARSDYYGDYGFAY	BBBABALAAEBAB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV1-82*01	100.0	Mo_IGHV1-82*01	100.0	H4	8	H4-8-1	18	ADKSSSTA	BBAAALBB
G	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-12*01	100.0	Mo_IGKV3-12*01	93.3	L1	15	L1-15-*	-1	RASKSVSTsgysFMH	BBABBABBEABBBBB
G	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-12*01	100.0	Mo_IGKV3-12*01	100.0	L2	8	L2-8-1	19	YLASNLES	BLEABBBB
G	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-12*01	100.0	Mo_IGKV3-12*01	100.0	L3	9	L3-9-cis7-1	19	QHSRELPWT	BBAABBbBB
G	kappa	Mus.musculus.Homo.sapiens	Mo_IGKV3-12*01	100.0	Mo_IGKV3-12*01	100.0	L4	6	L4-6-1	18	GSGTDF	EBEABB
H	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV5-9*04	98.6	Mo_IGHV5-9*04	100.0	H1	13	H1-13-1	14	AASGFTFSSYTMS	BBBLBBAAABBBB
H	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV5-9*04	98.6	Mo_IGHV5-9*04	80.0	H2	10	H2-10-2	20	YISSGGGNTY	BBBAALABBB
H	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV5-9*04	98.6	Mo_IGHV5-9*04	50.0	H3	10	H3-10-*	-1	SRHRGNPFDY	BBBBEABBAB
H	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV5-9*04	98.6	Mo_IGHV5-9*04	87.5	H4	8	H4-8-1	12	RDNARNTL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022