PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5N7W

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV1-46*02	94.5	Mo_IGHV1-55*01	84.6	H1	13	H1-13-1	7	KASGYTFSSYWIA	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV1-46*02	94.5	Mo_IGHV1-55*01	80.0	H2	10	H2-10-1	11	EILPGSGSTN	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV1-46*02	94.5	Hu_IGHV1-46*02	100.0	H3	12	H3-12-1	16	ARFPYYYGNWDV	BBBBAAALBBAB
A	heavy	Homo.sapiens	Hu_IGHV1-46*02	94.5	Hu_IGHV1-46*02	87.5	H4	8	H4-8-1	4	ADTSTSTV	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.6	Mo_IGKV10-94*03	72.7	L1	11	L1-11-2	6	QASQDIWWYLN	BBABBALLBBB
B	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.6	Mo_IGKV10-94*03	100.0	L2	8	L2-8-1	6	YYTSRLHS	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.6	Hu_IGKV1-33*01	57.1	L3	9	L3-9-cis7-1	8	QQGFYLPWT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.6	Hu_IGKV1-33*01	83.3	L4	6	L4-6-1	10	GSGTDY	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-46*02	94.5	Mo_IGHV1-55*01	84.6	H1	13	H1-13-1	7	KASGYTFSSYWIA	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-46*02	94.5	Mo_IGHV1-55*01	80.0	H2	10	H2-10-1	9	EILPGSGSTN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-46*02	94.5	Hu_IGHV1-46*02	100.0	H3	12	H3-12-1	17	ARFPYYYGNWDV	BBBBAAALBBAB
H	heavy	Homo.sapiens	Hu_IGHV1-46*02	94.5	Hu_IGHV1-46*02	87.5	H4	8	H4-8-1	5	ADTSTSTV	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.6	Mo_IGKV10-94*03	72.7	L1	11	L1-11-2	6	QASQDIWWYLN	BBABBALLBBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.6	Mo_IGKV10-94*03	100.0	L2	8	L2-8-1	5	YYTSRLHS	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.6	Hu_IGKV1-33*01	57.1	L3	9	L3-9-cis7-1	8	QQGFYLPWT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-33*01	98.6	Hu_IGKV1-33*01	83.3	L4	6	L4-6-1	8	GSGTDY	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022