PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5MVJ

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	76.9	H1	13	H1-13-1	11	KASGYIFTDYVIS	BBBLBBAAABBBB
A	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	80.0	H2	10	H2-10-1	11	EIFPRSGSTY	BBBAAALBBB
A	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	100.0	H3	13	H3-13-*	-1	ARDYYGTSFAMDY	BBBBBLAALBBAB
A	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	75.0	H4	8	H4-8-1	15	ADKSSNTA	BBAAALBB
B	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L1	17	L1-17-*	-1	KSSQSLlnsrtrKNYLA	BBABBABBAABBBBBBB
B	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L2	8	L2-8-1	11	YWASTRES	BLLABBBB
B	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	66.7	L3	8	L3-8-1	11	KQSFYLRT	BBAABEBB
B	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L4	6	L4-6-1	11	GSGTDF	EBEABB
C	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	76.9	H1	13	H1-13-1	10	KASGYIFTDYVIS	BBBLBBAAABBBB
C	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	80.0	H2	10	H2-10-1	12	EIFPRSGSTY	BBBAAALBBB
C	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	100.0	H3	13	H3-13-*	-1	ARDYYGTSFAMDY	BBBBBLAALBBAB
C	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	75.0	H4	8	H4-8-1	11	ADKSSNTA	BBAAALBB
D	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L1	17	L1-17-*	-1	KSSQSLlnsrtrKNYLA	BBABBABBAABBBBBBB
D	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L2	8	L2-8-1	10	YWASTRES	BLEABBBB
D	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	66.7	L3	8	L3-8-1	8	KQSFYLRT	BBAABEBB
D	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
E	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	76.9	H1	13	H1-13-1	8	KASGYIFTDYVIS	BBBLBBAAABBBB
E	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	80.0	H2	10	H2-10-1	8	EIFPRSGSTY	BBBAAALBBB
E	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	100.0	H3	13	H3-13-*	-1	ARDYYGTSFAMDY	BBBBBLAALBBAB
E	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	75.0	H4	8	H4-8-1	10	ADKSSNTA	BBAAALBB
F	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L1	17	L1-17-1	8	KSSQSLlnsrtrKNYLA	BBABBABBAAALBBBBB
F	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L2	8	L2-8-1	10	YWASTRES	BLLABBBB
F	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	66.7	L3	8	L3-8-1	8	KQSFYLRT	BBAABEBB
F	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L4	6	L4-6-1	11	GSGTDF	EBEABB
H	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	76.9	H1	13	H1-13-1	10	KASGYIFTDYVIS	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	80.0	H2	10	H2-10-1	9	EIFPRSGSTY	BBBAAALBBB
H	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	100.0	H3	13	H3-13-*	-1	ARDYYGTSFAMDY	BBBBBLAALBBAB
H	heavy	Mus.musculus	Mo_IGHV1-75*01	89.0	Mo_IGHV1-75*01	75.0	H4	8	H4-8-1	13	ADKSSNTA	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L1	17	L1-17-1	9	KSSQSLlnsrtrKNYLA	BBABBABBAAALBBBBB
L	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L2	8	L2-8-1	12	YWASTRES	BLLABBBB
L	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	66.7	L3	8	L3-8-1	9	KQSFYLRT	BBAABEBB
L	kappa	Mus.musculus	Mo_IGKV8-21*01	100.0	Mo_IGKV8-21*01	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022