PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5MHR

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
G	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L1	12	L1-12-1	6	SASSSISsNYLH	BBABBBBAAABB
G	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	87.5	L2	8	L2-8-1	7	YRTSKLAS	BLLABBBB
G	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	75.0	L3	8	L3-8-3	8	QQGSSIYT	BBAABBBB
G	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L4	6	L4-6-1	11	GSGTSY	EBEABB
H	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L1	12	L1-12-1	5	SASSSISsNYLH	BBABBBBAAABB
H	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	87.5	L2	8	L2-8-1	5	YRTSKLAS	BLLABBBB
H	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	75.0	L3	8	L3-8-3	8	QQGSSIYT	BBAABBBB
H	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L4	6	L4-6-1	8	GSGTSY	EBEABB
I	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYTMN	BBBLBABAABBBB
I	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H2	10	H2-10-1	23	LINPYNDGPS	BBBAAALBBB
I	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H3	14	H3-14-*	-1	AIHYYGISYWYFDV	BBBAAAAAALBBAB
I	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	100.0	H4	8	H4-8-1	6	VDKSSSTA	BBAAALBB
J	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L1	12	L1-12-1	7	SASSSISsNYLH	BBABBBBAAABB
J	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	87.5	L2	8	L2-8-1	7	YRTSKLAS	BLEABBBB
J	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	75.0	L3	8	L3-8-3	8	QQGSSIYT	BBAABBBB
J	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L4	6	L4-6-1	9	GSGTSY	EBEABB
K	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYTMN	BBBLBABAABBBB
K	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H2	10	H2-10-1	26	LINPYNDGPS	BBBAAALBBB
K	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H3	14	H3-14-*	-1	AIHYYGISYWYFDV	BBBAAAAAALBBAB
K	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	100.0	H4	8	H4-8-1	7	VDKSSSTA	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L1	12	L1-12-1	7	SASSSISsNYLH	BBABBBBAAABB
L	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	87.5	L2	8	L2-8-1	7	YRTSKLAS	BLEABBBB
L	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	75.0	L3	8	L3-8-3	7	QQGSSIYT	BBAABBBB
L	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L4	6	L4-6-1	9	GSGTSY	EBEABB
M	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYTMN	BBBLBABAABBBB
M	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H2	10	H2-10-*	-1	LINPYNDGPS	BBBAABABBB
M	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H3	14	H3-14-*	-1	AIHYYGISYWYFDV	BBBAAAAAALBBAB
M	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	100.0	H4	8	H4-8-1	7	VDKSSSTA	BBAAALBB
N	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYTMN	BBBLBABAABBBB
N	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H2	10	H2-10-*	-1	LINPYNDGPS	BBBAABABBB
N	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H3	14	H3-14-*	-1	AIHYYGISYWYFDV	BBBBLAAAALBBAB
N	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	100.0	H4	8	H4-8-1	7	VDKSSSTA	BBAAALBB
O	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L1	12	L1-12-1	8	SASSSISsNYLH	BBABBBBAAABB
O	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	87.5	L2	8	L2-8-1	7	YRTSKLAS	BLLABBBB
O	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	75.0	L3	8	L3-8-3	10	QQGSSIYT	BBAABBBB
O	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L4	6	L4-6-1	14	GSGTSY	EBEABB
P	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYTMN	BBBLBABAABBBB
P	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H2	10	H2-10-1	26	LINPYNDGPS	BBBAAALBBB
P	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H3	14	H3-14-*	-1	AIHYYGISYWYFDV	BBBAAAAAALBBAB
P	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	100.0	H4	8	H4-8-1	7	VDKSSSTA	BBAAALBB
Q	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L1	12	L1-12-1	7	SASSSISsNYLH	BBABBBBAAABB
Q	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	87.5	L2	8	L2-8-1	9	YRTSKLAS	BLEABBBB
Q	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	75.0	L3	8	L3-8-3	7	QQGSSIYT	BBAABBBB
Q	kappa	Mus.musculus	Mo_IGKV4-91*01	97.1	Mo_IGKV4-91*01	100.0	L4	6	L4-6-1	9	GSGTSY	EBEABB
R	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	92.3	H1	13	H1-13-*	-1	KASGYSFTGYTMN	BBBLBABAABBBB
R	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H2	10	H2-10-1	25	LINPYNDGPS	BBBAAALBBB
R	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	50.0	H3	14	H3-14-*	-1	AIHYYGISYWYFDV	BBBAAAAAALBBAB
R	heavy	Mus.musculus	Mo_IGHV1-37*01	93.2	Mo_IGHV1-37*01	100.0	H4	8	H4-8-1	8	VDKSSSTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022