PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5IIE

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV2-5*08	83.6	Mo_IGHV8-12*01	60.0	H1	15	H1-15-2	19	SFSGFSLrsSDTAVV	BBBLBBAABAABBBB
A	heavy	Homo.sapiens	Hu_IGHV2-5*08	83.6	Mo_IGHV8-12*01	55.6	H2	9	H2-9-1	17	AIYWDDVEH	BBBAALBBB
A	heavy	Homo.sapiens	Hu_IGHV2-5*08	83.6	Hu_IGHV2-5*08	0.0	H3	17	H3-17-*	-1	GRVRFVsggYYTDRIDS
A	heavy	Homo.sapiens	Hu_IGHV2-5*08	83.6	Hu_IGHV2-5*08	37.5	H4	8	H4-8-1	11	KDSPNSLV	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	91.2	Mo_IGLV4*01	30.8	L1	13	L1-13-1	22	AGTKSNIGDCSVS	BEBAAAAAABBBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	91.2	Mo_IGLV4*01	62.5	L2	8	L2-8-*	-1	YQNNNRPS	BLLABBBA
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	91.2	Hu_IGLV1-40*01	66.7	L3	11	L3-11-1	13	LSYDTSFSGWR	BBBBAAALBBB
B	lambda	Homo.sapiens	Hu_IGLV1-40*01	91.2	Hu_IGLV1-40*01	100.0	L4	6	L4-6-2	15	KSGTSA	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV2-5*08	83.6	Mo_IGHV8-12*01	60.0	H1	15	H1-15-2	17	SFSGFSLrsSDTAVV	BBBLBBAABAABBBB
H	heavy	Homo.sapiens	Hu_IGHV2-5*08	83.6	Mo_IGHV8-12*01	55.6	H2	9	H2-9-1	18	AIYWDDVEH	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV2-5*08	83.6	Hu_IGHV2-5*08	0.0	H3	17	H3-17-*	-1	GRVRFVsggYYTDRIDS
H	heavy	Homo.sapiens	Hu_IGHV2-5*08	83.6	Hu_IGHV2-5*08	37.5	H4	8	H4-8-1	14	KDSPNSLV	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	91.2	Mo_IGLV4*01	30.8	L1	13	L1-13-1	14	AGTKSNIGDCSVS	BBBAAAAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	91.2	Mo_IGLV4*01	62.5	L2	8	L2-8-1	9	YQNNNRPS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	91.2	Hu_IGLV1-40*01	66.7	L3	11	L3-11-1	10	LSYDTSFSGWR	BBBBAAALEBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	91.2	Hu_IGLV1-40*01	100.0	L4	6	L4-6-2	10	KSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022